Asymmetric hydrogenation of aromatic ketones catalyzed by achiral monophosphine TPPTS-stabilized Ru in ionic liquids was written by Wang, Jinbo;Feng, Jian;Qin, Ruixiang;Fu, Haiyan;Yuan, Maolin;Chen, Hua;Li, Xianjun. And the article was included in Tetrahedron: Asymmetry in 2007.Recommanded Product: 171032-87-4 This article mentions the following:
Ruthenium nanoparticles generated from ruthenium trichloride and TPPTS [3-(NaSO3)C6H4]3P and the nonracemic ligand I together act as a catalyst for the enantioselective hydrogenation of aralkyl ketones RCOR1 (R = Ph, 2-BrC6H4, 2-ClC6H4, 2-FC6H4, 2-MeOC6H4, 4-F3CC6H4, 4-MeOC6H4; R1 = Me, Et) in mixtures of imidazolium ionic liquids and water to give nonracemic aralkyl alcs. RCH(OH)R1 in 48-100% conversions and in 45-85% ee. The effect of temperature, of potassium hydroxide and water concentrations, and of ionic liquid on enantioselectivity and conversion are determined The aralkyl alcs. are easily separated from the catalyst by simple extraction with n-hexane. The catalyst solution in the ionic liquid can be reused six times with some loss in conversion but little loss in enantioselectivity. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Recommanded Product: 171032-87-4).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: 171032-87-4
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts