Inversion of stereochemistry in the asymmetric transfer hydrogenation of ketones performed in tap water and in open-vessel was written by Xu, Zhou;Mao, Jincheng;Zhang, Yawen;Guo, Jun;Zhu, Jinlong. And the article was included in Catalysis Communications in 2008.HPLC of Formula: 120121-01-9 This article mentions the following:
The readily available (1R,2S)-1-amino-2-indanol (I) was employed into the [RuCl2(p-cymene)]2-catalyzed asym. transfer hydrogenation of prochiral ketones performed in tap water. The reaction was conducted in open vessel at room temperature, providing moderate to good conversions and enantioselectivities. In addition, the relationship between the structure of the chiral ligand and the catalytic efficiency was studied. Surprisingly, N-substitution of I led to the inversion of the configuration of the product under the same conditions. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9HPLC of Formula: 120121-01-9).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.HPLC of Formula: 120121-01-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts