Automated solid sample dissolution coupled with sugaring-out homogenous liquid-liquid extraction. Application for the analysis of throat lozenge samples was written by Shishov, Andrey;Nechaeva, Daria;Moskvin, Leonid;Andruch, Vasil;Bulatov, Andrey. And the article was included in Journal of Molecular Liquids in 2017.Product Details of 1777-82-8 This article mentions the following:
A novel automated procedure for anal. of solid samples based on the online dissolution of solid sample and sugaring-out reagent in water-acetonitrile mixture coupled with sugaring-out homogenous liquid-liquid extraction was developed. The procedure was performed in a mixing chamber of a stepwise injection anal. manifold. The performance of the suggested approach was demonstrated by the determination of 2,4-dichlorobenzyl alc., amylmetacresol, Yellow Orange S, Azo Rubine and Ponceau 4R in pharmaceutical samples. After phase separation, the upper acetonitrile phase containing 2,4-dichlorobenzyl alc., amylmetacresol and lower aqueous phase containing artificial dyes were sequentially analyzed. Under optimal exptl. conditions the linear ranges were found to be 0.1-10 mg L– 1 for 2,4 dichlorobenzyl alc., 0.5-50 mg L– 1 for amylmetacresol, and 1-100 mg L– 1 for artificial dyes. The sample throughput was 10 h– 1. The proposed method was successfully applied for the automated anal. of com. throat lozenges and the anal. results agreed fairly well with the results obtained by reference HPLC-UV method. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Product Details of 1777-82-8).
(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Product Details of 1777-82-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts