Asymmetric reduction of acetophenone analogues by Alternaria alternata using ram horn peptone was written by Kurbanoglu, Esabi B.;Zilbeyaz, Kani;Kurbanoglu, Namudar I.;Kilic, Hamdullah. And the article was included in Tetrahedron: Asymmetry in 2007.Safety of (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:
Alternaria alternata EBK-4 fungus isolated from a plant sample was evaluated for the asym. reduction of acetophenone analogs. In a previous study, this isolate was used for the reduction of acetophenone to 1-phenylethanol in excellent enantiomeric excess. The substituted acetophenones were converted to the corresponding optically active alc. by A. alternata EBK-4 under optimized conditions in up to >99% enantiomeric excess (ee). This is the first report on the enantiomeric reduction of acetophenone analogs by A. alternata using ram horn peptone from waste material. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Safety of (S)-1-(2-Fluorophenyl)ethanol).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of (S)-1-(2-Fluorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts