Hydrogenation and Reductive Amination of Aldehydes using Triphos Ruthenium Catalysts was written by Christie, Francesca;Zanotti-Gerosa, Antonio;Grainger, Damian. And the article was included in ChemCatChem in 2018.HPLC of Formula: 1777-82-8 This article mentions the following:
An air-stable and readily accessible ruthenium dihydride complex catalyzes aldehyde hydrogenation under neutral conditions. A high activity has been shown in a number of examples, and solvent-free conditions are also applicable, which favors industrial-scale applications. The catalyst has also been demonstrated to be active at low catalyst loadings for the reductive amination of aldehydes under mildly acidic conditions. A number of examples of chemoselectivity challenges are also presented in which the catalyst does not reduce carbon-halogen groups, alkene or ketone functionality. The advantage of using the pre-formed complex, Triphos-Ru(CO)H2 (1), over in situ formed catalysts from Triphos and Ru(acac)3 (acac=acetylacetonate) is also shown in terms of both chemoselectivity and activity, in particular this can be seen if low reaction temperatures are used. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8HPLC of Formula: 1777-82-8).
(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.HPLC of Formula: 1777-82-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts