Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents was written by Miller, John F.;Turner, Elizabeth M.;Gudmundsson, Kristjan S.;Jenkinson, Stephen;Spaltenstein, Andrew;Thomson, Michael;Wheelan, Pat. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2010.Application of 142253-56-3 This article mentions the following:
The lead optimization of a series of N-substituted benzimidazole CXCR4 antagonists is described. Side chain modifications and stereochem. optimization led to substantial improvements in potency and protein shift to afford compounds with low nanomolar anti-HIV activity. In the experiment, the researchers used many compounds, for example, 1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3Application of 142253-56-3).
1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application of 142253-56-3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts