Metabolism of fenitrothion in birds was written by Mihara, Kazumasa;Misaki, Yoshinori;Miyamoto, Junshi. And the article was included in Nippon Noyaku Gakkaishi in 1979.Reference of 60463-12-9 This article mentions the following:
Within 24 h after oral administration of 14C-labeled fenitrothion (I) [122-14-5] to female Japanese quails singly at 5 mg/kg or to White Leghorn hens for 7 days at 2 mg/kg/day, 97-99% of the applied 14C was excreted without accumulation of 14C in any tissue. At most 0.2% of the applied 14C was eliminated into eggs. Of >18 metabolites in the excreta, 14 were identified. The quails and hens excreted 70.5 and 50.8%, resp., of the applied 14C as 3-methyl-4-nitrophenol [2581-34-2] including its sulfate [60463-13-0]. Only 10-15% of the applied 14C was excreted as O-demthylation product of I [4321-64-6] and fenitrooxon (II) [2255-17-6], whereas 13-18% was excreted as 3-hydroxymethyl-4-nitrophenol [60463-12-9] and β-glucuronide [72041-46-4]. Hen, pheasant, and quail liver enzyme preparations had higher activities of oxidizing II to dimethyl 3-hydroxymethyl-4-nitrophenyl phosphate [66558-68-7] than those of mammals, but had much lower activities of demethylating I at the P-O-Me linkage. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9Reference of 60463-12-9).
3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Reference of 60463-12-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts