Asymmetric cross Rauhut-Currier reactions of vinyl ketones with carbonyl para-quinone methides via phosphine catalysis was written by Lu, Yue;He, Ningtao;Miao, Xiaohe;Wang, De. And the article was included in Organic Chemistry Frontiers in 2022.Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol This article mentions the following:
Novel cross Rauhut-Currier reactions involving chiral phosphine catalysis between vinyl ketones and terminal-carbonyl-substituted para-quinone methides have been presented. This reaction approach showed broad substrate scope compatibility and moderate-to-excellent enantioselectivity control. The multifunctional products could be easily transformed to important and useful skeletons. Moreover, natural-product and drug derivatives were well tolerated in this methodol., exhibiting the promising applications of this reaction approach. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol).
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts