SO2F2 mediated dehydrative cross-coupling of alcohols with electron-deficient olefins in DMSO using a Pd-catalyst: one-pot transformation of alcohols into 1,3-dienes was written by Lekkala, Revathi;Lekkala, Ravindar;Moku, Balakrishna;Qin, Hua-Li. And the article was included in Organic Chemistry Frontiers in 2019.COA of Formula: C9H9F3O This article mentions the following:
A Pd-catalyzed, SO2F2 mediated dehydrative cross-coupling reaction of alcs. with acrylates for the construction of 1,3-dienes I [Ar = Ph, 2-MeC6H4, 1-naphthyl, 2-thienyl, etc.; R = CO2Me, CO2Et, C(O)Et, etc.; stereo = E/E] was developed. The reaction proceeded efficiently under mild conditions and tolerated a wide range of functional groups. This new reaction provided a strategically distinct approach to highly valuable 1,3-diene derivatives from readily available and abundant alcs. In the experiment, the researchers used many compounds, for example, 2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6COA of Formula: C9H9F3O).
2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C9H9F3O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts