Davis-Beirut Reaction: A Photochemical Bronsted Acid Catalyzed Route to N-Aryl 2H-Indazoles was written by Kraemer, Niklas;Li, Clarabella J.;Zhu, Jie S.;Larach, Julio M.;Tsui, Ka Yi;Tantillo, Dean J.;Haddadin, Makhluf J.;Kurth, Mark J.. And the article was included in Organic Letters in 2019.HPLC of Formula: 80866-76-8 This article mentions the following:
The Davis-Beirut reaction provides access to 2H-indazoles from aromatic nitro compounds However, N-aryl targets have been traditionally challenging to access due to competitive alternate reaction pathways. Previously, the key nitroso imine intermediate was generated under alk. conditions, but as reported here, the photochem. of o-nitrobenzyl alcs. empowered Bronsted acid catalyzed conditions for accessing N-aryl targets. Anilines and alkyl amines give different outcomes under optimized conditions; the proposed mechanism was studied using quantum chem. calculations In the experiment, the researchers used many compounds, for example, (3-Methyl-2-nitrophenyl)methanol (cas: 80866-76-8HPLC of Formula: 80866-76-8).
(3-Methyl-2-nitrophenyl)methanol (cas: 80866-76-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.HPLC of Formula: 80866-76-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts