The ethanol-extracted polysaccharide from Cynanchum paniculatum: Optimization, structure, antioxidant and antitumor effects was written by Ji, Hai-yu;Dai, Ke-yao;Liu, Chao;Yu, Juan;Liu, An-jun;Chen, Ye-fu. And the article was included in Industrial Crops and Products in 2022.Quality Control of (2R,3S)-rel-Butane-1,2,3,4-tetraol This article mentions the following:
Cynanchum paniculatum has been applied for various diseases treatments, however, the polysaccharide components especially extracted using ethanol were rarely researched. In this study, ethanol solution with volume fraction of 75% was used for C. paniculatum polysaccharide preparation, and the extraction process optimization, structural characteristics, and bioactivities anal. were investigated. These results showed that extraction yield reached to 4.79 ± 0.24% under extraction temperature of 60°C, extraction time of 4.5 h, liquid/solid ratio of 30 mL/g. Chem. constitutions and monosaccharide compositions, mol. weight determination results showed that the polysaccharide was mainly composed of glucose and xylose with a molar ratio of 1.00:0.63 (carbohydrate content of 94.91%, mol. weight of 5.1 kDa). Periodate oxidation, smith degradation, methylation, fourier transform IR spectra and NMR anal. demonstrated that the glycosidic bonds configurations were mainly comprised of (1→2)-α–Glcp (39.86%), (1→2,4)-α–Glcp (10.32%) and (1→4)-β–Xylp (29.58%). The bioactivities determination experiments results suggested that the polysaccharide exhibited strong antioxidant activities and antitumor effects both in vitro and in vivo. These data indicated that the ethanol-extracted polysaccharide from C. paniculatum holds great application prospect as a novel bioactive adjuvant in the future due to the feasibility of industrial production In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Quality Control of (2R,3S)-rel-Butane-1,2,3,4-tetraol).
(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of (2R,3S)-rel-Butane-1,2,3,4-tetraol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts