Cyclization Reaction of 4-Acyl-1-sulfonyl-1,2,3-triazoles Possessing Phenyl Rings through Generation of Electron-deficient Carbenoids was written by Zhao, Qiang;Miura, Tomoya;Murakami, Masahiro. And the article was included in Chemistry Letters in 2019.SDS of cas: 2968-93-6 This article mentions the following:
A rhodium-catalyzed cyclization reaction of 4-acyl-1-sulfonyl-1,2,3-triazoles was reported for the synthesis of 2-indanone derivatives such as I [R = H, 5-Me, 6-OMe, etc. ; R1 = Ms, Ts; R2 = H, Ph, (CH2)2Ph]. Generated acceptor/acceptor carbenoids underwent cyclization by reacting either with a Ph ring through electrophilic aromatic substitution or with a benzylic C-H bond through insertion depending on the length of the carbon chain. In the experiment, the researchers used many compounds, for example, 2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6SDS of cas: 2968-93-6).
2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.SDS of cas: 2968-93-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts