Selenium-Electrocatalytic Cyclization of 2-Vinylanilides towards Indoles of Peptide Labeling was written by Zeng, Shaogao;Fang, Songlin;Cai, Haiping;Wang, Dong;Liu, Weiliang;Hu, Xinwei;Sun, Pinghua;Ruan, Zhixiong. And the article was included in Chemistry – An Asian Journal in 2022.Computed Properties of C10H20O This article mentions the following:
A novel selenium-electrocatalytic intramol. cyclization of 2-vinylanilides for synthesis of functionalized indoles and azaindoles was developed. In contrast to the previous synthetic methods, this sustainable protocol enabled unparalleled broad substrates scope for viable indoles with highly functional and sensitive groups by employing recyclable selenium catalyst, under mild, metal- and external-oxidant-free conditions. The approach was used to the late-stage modification of complex bioactive mol. system, thereby setting the stage for versatile syntheses of decorated indoles with peptide labeling. A plausible catalytic pathway were proposed. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Computed Properties of C10H20O).
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C10H20O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts