Gold-Catalyzed Cyclization of Ynones Involving cis-Hydrofunctionalizations: Rapid Assembly of C-, O-, or S-Functionalized Pyrroles by a Single Methodology was written by Pei, Miaomiao;Wang, Ali;Xie, Xin;Hu, Xiaoping;Liu, Yuanhong. And the article was included in Organic Letters in 2022.Synthetic Route of C10H20O This article mentions the following:
A gold-catalyzed cyclization of conjugated ynones with various nucleophiles such as indoles, alcs. and thiols was developed. The reaction provided a new and efficient protocol for the synthesis of functionalized pyrroles with wide versatility and functional group compatibility. Remarkably, indolyl, alkoxy or sulfenyl pyrroles, all could be constructed efficiently by this single methodol. In addition, cis-hydrofunctionalizations of ynones were involved in these reactions. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Synthetic Route of C10H20O).
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Synthetic Route of C10H20O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts