Syntheses employing pyridyllithium reagents. New routes to 2,6-disubstituted pyridines and 6,6’disubstituted 2,2′-bipyridyls was written by Parks, J. E.;Wagner, B. E.;Holm, R. H.. And the article was included in Journal of Organometallic Chemistry in 1973.Application In Synthesis of 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine This article mentions the following:
New 2,6-disubstituted pyridine derivatives were prepared using 6-bromo-2-lithiopyridine (I) as an intermediate. Thus, I and MeCONMe2 gave 2-acetyl-6-bromopyridine. Subsequent replacement of the 6-bromine can be effected by metal-halogen exchange or other reactions in some cases. Reactions of 6-lithio-2,2′-bipyridyl and 6,6′-dilithio-2,2′-bipyridyl are described. CuCl2 was an effective coupling agent for lithiopyridine reagents, allowing facile and high yield syntheses of substituted 2,2′-bipyridyls. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Application In Synthesis of 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine).
2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts