A Convenient and Stable Heterogeneous Nickel Catalyst for Hydrodehalogenation of Aryl Halides Using Molecular Hydrogen was written by Leonard, David K.;Ryabchuk, Pavel;Anwar, Muhammad;Dastgir, Sarim;Junge, Kathrin;Beller, Matthias. And the article was included in ChemSusChem in 2022.Category: alcohols-buliding-blocks This article mentions the following:
In this study, a nickel-based catalyst supported on titania (Ni-phen@TiO2-800) was prepared and used as a safe alternative to pyrophoric Raney-nickel. The catalyst was prepared in a straightforward fashion by deposition of nickel(II)/1,10-phenanthroline on titania, followed by pyrolysis. The catalytic material, which was characterized by SEM, TEM, XRD and XPS, consisted of nickel nanoparticles covered with N-doped carbon layers. By using design of experiments (DoE), this nanostructured catalyst was found to be proficient for the facile and selective hydrodehalogenation of a diverse range of substrates bearing C-I, C-Br, or C-Cl bonds afforded aromatic hydrocarbons R-H [R = 1-naphthyl, 4-H2NC6H4, 4-CO2MeC6H4, etc.] (>30 examples). The practicality of this catalyst system was demonstrated by the dehalogenation of environmentally hazardous and polyhalogenated substrates atrazine, tetrabromobisphenol A, tetrachlorobenzene and a polybrominated di-Ph ether (PBDE). In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Category: alcohols-buliding-blocks).
(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts