Determination of terpin hydrate in elixirs by gas chromatography was written by Kurlansik, Leon;Damon, Carolyn;Klein, Hannah;Salim, Edward F.. And the article was included in Journal of Pharmaceutical Sciences in 1967.Application In Synthesis of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:
The determination of terpin hydrate by gas chromatographic anal. (CA 67: 94052b) has been extended to the assay of terpin hydrate in official elixirs after isolation of the drug in relatively pure form. The procedure is an improvement over existing methods in specificity and reproducibility. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Application In Synthesis of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).
rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts