Reinvestigating FeBr3-Catalyzed Alcohol Oxidation with H2O2: Is High-valent Iron Species (HIS) or Reactive Brominating Species (RBS) Responsible for Alcohol Oxidation? was written by He, Chenxi;Ma, Foqing;Zhang, Wei;Tong, Rongbiao. And the article was included in Organic Letters in 2022.Category: alcohols-buliding-blocks This article mentions the following:
The in-situ generated RBS from the related FeBr2/H2O2 or CeBr3/H2O2 systems, (2) This results of a series of controlled experiments, and (3) some related RBS-based precedents (NBS, NBA, or Br2) showing similar high oxidation selectivity of secondary over primary alcs. These studies enable to discover that RBS from CeBr3/H2O2 was much more efficient for the oxidation of secondary and benzylic alcs., which represents a new green protocol for selective oxidation of alcs. to carbonyls. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Category: alcohols-buliding-blocks).
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts