Branched poly (trimethylphosphonium ethylacrylate-co-PEGA) by RAFT: alternative to cationic polyammoniums for nucleic acid complexation was written by Cook, Alexander B.;Peltier, Raoul;Barlow, Tammie R.;Tanaka, Joji;Burns, James A.;Perrier, Sebastien. And the article was included in Journal of Interdisciplinary Nanomedicine in 2018.SDS of cas: 4074-88-8 This article mentions the following:
Cationic and highly branched poly (trimethylphosphonium ethylacrylate-co-poly (ethylene glycol) acrylate) (p (TMPEA-co-PEGA)), and its ammonium equivalent, have been synthesized from post-polymerization modification of a poly (bromo ethylacrylate-co-poly (ethylene glycol) acrylate) (p (BEA-co-PEGA)) precursor polymer produced using reversible addition fragmentation chain transfer (RAFT) polymerization The cationic polymers were evaluated for their ability to complex nucleic acids, their in vitro cytotoxicity and their GFP pDNA transfection efficiency. The results show RAFT copolymerization of BEA and PEGA is a simple route to polyphosphoniums showing reduced cytotoxicities and higher transfection efficiencies than their polyammonium alternatives. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8SDS of cas: 4074-88-8).
Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.SDS of cas: 4074-88-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts