The nuclear magnetic resonance spectra of pyridine derivatives was written by Bruegel, W.. And the article was included in Zeitschrift fuer Elektrochemie und Angewandte Physikalische Chemie in 1962.Computed Properties of C7H9NO This article mentions the following:
The spectra of 154 pyridine derivatives were examined at 40 or 60 Mc. Liquids were run pure; solids were dissolved in Me2SO, which caused a small upfield shift in chem. shifts, but had little or no effect on the coupling constants Spectra were analyzed for chem. shifts and coupling constants The compounds studied contained 1, 2, or 3 substituents. With the exception of strong electron donors in the 3 position, substituents had little effect on coupling constants The effect of such groups as NH2 or COR in the 3 position was attributed to resonance of such groups with the ring. The ranges observed for the various coupling constants are as follows: J23, 4.8-5.5; J24, 0-2.5; J25, 0-1.4; J26, 0-0.6; J34, 7.2-9.1; J35, 0.5-1.8; J36, 0.4-2.3; J45, 6.8-8.8; J46, 1.0-2.5; J56, 4.0-5.5. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Computed Properties of C7H9NO).
6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Computed Properties of C7H9NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts