Gas-liquid analysis of terpenes in therapeutic preparations was written by Zen’ko, I. V.;Pogodina, L. I.;Pertsovskii, A. L.;Voitekhovskaya, G. I.. And the article was included in Vestsi Akademii Navuk BSSR, Seryya Khimichnykh Navuk in 1980.Electric Literature of C10H22O3 This article mentions the following:
Stationary phases of different polarity were used in the gas chromatog. determination of camphor (I) [76-22-2], bromocamphor [76-29-9], menthol [89-78-1], thymol [89-83-8], terpin hydrate [2451-01-6], validol [28221-20-7], and α- [141-27-5] and β-citral [106-26-3] in formulations containing many other drugs. Glass columns of silanized Chromaton N-AW coated with 0.5% polyethylene glycol 20M and stationary phases of 10% Apiezon L or 10% Reoplex 400 and flame ionization detection were used. Except for thymol, for which a 1-8% solution was used, the other terpenes were analyzed as 0.25-2.5% solutions; the relative error was 1-3.2%. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Electric Literature of C10H22O3).
rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Electric Literature of C10H22O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts