Allergic contact dermatitis caused by 1,6-hexanediol diacrylate in a hospital wristband was written by van Amerongen, Cynthia C. A.;Dahlin, Jakob;Isaksson, Marlene;Schuttelaar, Marie L. A.. And the article was included in Contact Dermatitis in 2019.Category: alcohols-buliding-blocks This article mentions the following:
1,6-Hexanediol diacrylate (1,6-HDDA) is a multifunctional acrylate and a potent sensitizer. To report a case of allergic contact dermatitis caused by 1,6-HDDA in a hospital wristband. A male patient presented with eczema on his wrist where he had worn a hospital wristband. Patch testing was performed with our extended European baseline series, addnl. series, and pieces of the hospital wristband. Thin-layer chromatog. (TLC) was performed with extracts from the wristband and gas chromatog.-mass spectrometry was used for chem. anal. Pos. reactions were found to pieces of the wristband, including adhesive rim (+++), inside (+++), and outside (++); to multiple allergens in the (meth)acrylates series; and to extracts of the wristband in acetone and ethanol. Chem. anal. of the ethanol extract showed presence of lauryl acrylate and 1,6-HDDA. Patch testing with TLC strips and subsequent chem. anal. showed that the substance causing the strongest reaction was 1,6-HDDA, to which the patient had a confirmed pos. patch test reaction. 1,6-HDDA was identified as the culprit allergen responsible for allergic contact dermatitis caused by the hospital wristband. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Category: alcohols-buliding-blocks).
Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts