Catalytic Amination of β-(Hetero)arylethyl Ethers by Phosphazene Base t-Bu-P4 was written by Shigeno, Masanori;Nakamura, Ryutaro;Hayashi, Kazutoshi;Nozawa-Kumada, Kanako;Kondo, Yoshinori. And the article was included in Organic Letters in 2019.Recommanded Product: 2968-93-6 This article mentions the following:
The catalytic amination of β-(hetero)arylethyl ethers with amines using the organic superbase t-Bu-P4 to obtain β-(hetero)arylethylamines, is described. The reaction has a broad substrate scope and allows the transformations of electron-deficient and electron-neutral β-(hetero)arylethyl ethers with various amines including pyrrole, N-alkylaniline, diphenylamine, aniline, indole, and indoline derivatives Mechanistic studies indicate a two-reaction pathway of MeOH elimination from the substrate to form a (hetero)arylalkene followed by the hydroamination of the alkene. In the experiment, the researchers used many compounds, for example, 2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6Recommanded Product: 2968-93-6).
2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 2968-93-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts