Doherty, Simon et al. published their research in European Journal of Inorganic Chemistry in 2021 | CAS: 171032-87-4

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.SDS of cas: 171032-87-4

Arene-Immobilized Ru(II)/TsDPEN Complexes: Synthesis and Applications to the Asymmetric Transfer Hydrogenation of Ketones was written by Doherty, Simon;Knight, Julian G.;Alshaikh, Hind;Wilson, James;Waddell, Paul G.;Wills, Corinne;Dixon, Casey M.. And the article was included in European Journal of Inorganic Chemistry in 2021.SDS of cas: 171032-87-4 This article mentions the following:

The Noyori-Ikariya (arene)Ru(II)/TsDPEN precatalyst was anchored to amorphous SiO2 and DAVISIL through the η6-coordinated arene ligand via a straightforward synthesis and the derived systems, (arene)Ru(II)/TsDPEN@silica and (arene)Ru(II)/TsDPEN@DAVISIL, form highly efficient catalysts for the asym. transfer hydrogenation of a range of electron-rich and electron-poor aromatic ketones, giving good conversion and excellent ee’s under mild reaction conditions. Also, catalyst generated in situ immediately prior to addition of substrate and H donor, by reaction of SiO2-supported [(arene)RuCl2]2 with (S,S)-TsDPEN, was as efficient as that generated from its preformed counterpart [(arene)Ru{(S,S)-TsDPEN}Cl]@silica. Gratifyingly, the initial TOFs (up to 1085 h-1) and ee’s (96-97%) obtained with these catalysts either rivaled or outperformed those previously reported for catalysts supported by either SiO2 or polymer immobilized through one of the N atoms of TsDPEN. While the high ee’s were also maintained during recycle studies, the conversion dropped steadily over the 1st three runs due to gradual leaching of the Ru. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4SDS of cas: 171032-87-4).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.SDS of cas: 171032-87-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts