Complexes of pyridoxal thiosemicarbazones formed with vanadium(IV/V) and copper(II): Solution equilibrium and structure was written by Jakusch, Tamas;Kozma, Karoly;Enyedy, Eva A.;May, Nora V.;Roller, Alexander;Kowol, Christian R.;Keppler, Bernhard K.;Kiss, Tamas. And the article was included in Inorganica Chimica Acta in 2018.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
The stoichiometry and thermodn. stability of vanadium(IV/V) and copper(II) complexes of pyridoxal thiosemicarbazone and pyridoxal-N3,N3-dimethylthiosemicarbazone were determined by pH-potentiometry (VIVO), EPR (VIVO/CuII), UV-visible (CuII, VIVO and VV) and 51V NMR spectroscopy (VV) in 30% (weight/weight) DMSO/water solvent mixture In all cases, mono-ligand complexes are formed in different protonation states. In addition, the proton-dissociation constants of the ligands were also determined by pH-potentiometry, UV-visible and 1H NMR spectroscopy. The solid state structures of the monoprotonated forms (VVO2(L1H)×1.5H2O) (1) and (VVO2(L2H)×0.8H2O) (2) of the VV complexes were characterized by single-crystal x-ray diffraction anal. The mono-ligand complexes of CuII and VV are dominant at physiol. pH. With all studied metal ions the pyridoxal moiety of the ligand causes an extra deprotonation step between pH 4 and 7 due to the non-coordinating pyridine-NH+. The pyridoxal-containing ligands form somewhat more stable complexes with both VIVO and CuII ions than the reference compound salicylaldehyde thiosemicarbazone. Dimethylation of the terminal amino group gave VV and CuII complexes with even higher stability. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
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