The author of 《Chemoselective Synthesis of α-Amino-α-cyanophosphonates by Reductive Gem-Cyanation-Phosphonylation of Secondary Amides》 were Chen, Ting-Ting; Wang, Ai-E.; Huang, Pei-Qiang. And the article was published in Organic Letters in 2019. Related Products of 13325-10-5 The author mentioned the following in the article:
A novel approach to α-amino-α-cyanophosphonates was developed. The method features a Tf2O-mediated reductive geminal cyanation/phosphonylation of secondary amides. Mild reaction conditions, high bond-forming efficiency, inexpensive readily available starting materials, and good to excellent yields with wide functional group compatibility constitute the main advantages of this method. The protocol can be run on a gram scale. The experimental process involved the reaction of 4-Aminobutan-1-ol(cas: 13325-10-5Related Products of 13325-10-5)
4-Aminobutan-1-ol(cas: 13325-10-5) is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.Related Products of 13325-10-5
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