Wei, Dongyue; Yang, Peng; Yu, Chuanman; Zhao, Fengkai; Wang, Yilei; Peng, Zhihua published their research in Journal of Organic Chemistry in 2021. The article was titled 《N-Alkylation of Amines with Alcohols Catalyzed by Manganese(II) Chloride or Bromopentacarbonylmanganese(I)》.Product Details of 100-55-0 The article contains the following contents:
A manganese-catalyzed N-alkylation reaction of amines with alcs. via hydrogen autotransfer strategy was demonstrated. The developed practical catalytic system included an inexpensive, nontoxic, com. available MnCl2 or MnBr(CO)5 as the metal salt and triphenylphosphine as a ligand provided access to diverse aromatic, heteroaromatic, and aliphatic secondary amines in moderate-to-high yields. In addition, this operationally simple protocol was scalable to the gram level and suitable for synthesizing heterocycles such as indole and resveratrol-derived amines known to be active for Alzheimer’s disease. In the experiment, the researchers used 3-Pyridinemethanol(cas: 100-55-0Product Details of 100-55-0)
3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Product Details of 100-55-0
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts