《Fiber optic particle plasmon resonance immunosensor for rapid and sensitive detection of methamphetamine based on competitive inhibition》 was written by Chang, Ting-Chou; Chiang, Chang-Yue; Lin, Min-Hsiu; Chen, I-Kuang; Chau, Lai-Kwan; Hsu, Day-Shin; Shieh, Szu-Shan; Kuo, Chin-Jung; Wang, Shau-Chun; Chen, Yung-fou. Electric Literature of C6H15NO And the article was included in Microchemical Journal in 2020. The article conveys some information:
We report the study of methamphetamine (MA) sensing in urine samples using fiber optic particle plasmon resonance (FOPPR) biosensor. This approach is intended for on-site anal. of low-mol.-weight compounds High sensitivity detection of MA at ultra-low concentration is realized by using a competitive inhibition immunoreaction scheme based on the competition of free MA in solution for anti-MA mols. that bind to the bovine serum albumin (BSA)-MA conjugate on the gold nanoparticle surface. With the BSA-MA functionalized sensor fiber, in the presence of a fixed concentration of anti-MA and various concentrations of MA in sample, the change of transmitted light intensity through the sensor fiber relative to that in a buffer solution decreases when the MA concentration increases because of the inhibition effect of MA. Based on this sensing method, the MA-functionalized FOPPR biosensor is capable for determining the concentration of MA with high sensitivity and wide linear dynamic range of 1-1000 ng/mL. The limit of detection for MA is 0.16 ng/mL. In addition, the MA functionalized FOPPR biosensor can detect MA in diluted human urine samples without nonspecific adsorption interference.6-Aminohexan-1-ol(cas: 4048-33-3Electric Literature of C6H15NO) was used in this study.
6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Electric Literature of C6H15NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts