On February 27, 2020, Quattropani, Anna; Kulkarni, Santosh S.; Rakesh, Paul; Giri, Awadut Gajendra published a patent.Recommanded Product: (6-(Trifluoromethyl)pyridin-3-yl)methanol The title of the patent was Preparation of spiro compounds as glycosidase inhibitors. And the patent contained the following:
The invention relates to compounds of formula I, and pharmaceutically usable derivatives, solvates, salts, prodrugs, tautomers, enantiomers, racemates and stereoisomers thereof, including mixtures thereof in all ratios and compounds of formula I, wherein one or more H atoms may be replaced by D (deuterium) which are useful as glycosidase inhibitors, useful in the treatment of tauopathies and Alzheimer’s disease. Compounds of formula I wherein, R is (un)branched alkyl; L is CH2, NH2 and derivatives, N(CH2)0-2, etc.; Q1 is CH2, CO; Q2 is CH2 and CO; n = 0 – 2; A is benzothiazolyl, benzofuranyl, imidazolpyridyl, etc.; Z is H, halo, CN, OH, etc.; are claimed. The example compound II was prepared by condensation of 3-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione with 5-(1-chloroethyl)benzo[d]thiazole. Compounds I were evaluated for their glycosidase inhibtory activity (some data given). The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Recommanded Product: (6-(Trifluoromethyl)pyridin-3-yl)methanol
The Article related to piperazine preparation glycosidase inhibitor treatment tauopathy alzheimer, Heterocyclic Compounds (One Hetero Atom): Spiro Compounds With One Hetero Atom In Each Ring and other aspects.Recommanded Product: (6-(Trifluoromethyl)pyridin-3-yl)methanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts