Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 141699-55-0, formula is C8H15NO3, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. SDS of cas: 141699-55-0
Takhi, Mohamed;Sreenivas, Kandepu;Reddy, Chandrashekar K.;Munikumar, Mahadari;Praveena, Kolakota;Sudheer, Pabolu;Rao, Bandaru N. V. M.;Ramakanth, Gollamudi;Sivaranjani, Jampala;Mulik, Shardaprasad;Reddy, Yeruva R.;Narasimha Rao, Krishnamurthy;Pallavi, Rentala;Lakshminarasimhan, Anirudha;Panigrahi, Sunil K.;Antony, Thomas;Abdullah, Iskandar;Lee, Yean K.;Ramachandra, Murali;Yusof, Rohana;Rahman, Noorsaadah A.;Subramanya, Hosahalli research published 《 Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors》, the research content is summarized as follows. A novel and potent series of ene-amides featuring azetidines has been developed as FabI inhibitors active against drug resistant Gram-pos. pathogens particularly staphylococcal organisms. Most of the compounds from the series possessed excellent biochem. inhibition of Staphylococcus aureus FabI enzyme and whole cell activity against clin. relevant MRSA, MSSA and MRSE organisms which are responsible for significant morbidity and mortality in community as well as hospital settings. The binding mode of one of the leads, I, in Escherichia coli FabI enzyme was determined unambiguously using x-ray crystallog. The lead compounds displayed good metabolic stability in mice liver microsomes and pharmacokinetic profile in mice. The in vivo efficacy of lead AEA16 has been demonstrated in a lethal murine systemic infection model.
SDS of cas: 141699-55-0, Tert-butyl 3-hydroxyazetidine-1-carboxylate is a useful research compound. Its molecular formula is C8H15NO3 and its molecular weight is 173.21 g/mol. The purity is usually 95%.
Tert-butyl 3-hydroxyazetidine-1-carboxylate has been shown to be a good substrate for the preparation of N-protected amino alcohols and amines by the process of reductive amination. In this synthesis, tert-butyl azetidinium chloride is used as a catalyst in the reaction with sodium hydroxide. The tert-butyl group can be removed using ammonium hydroxide in the presence of a base such as triethylamine. This reaction can be performed on a large scale, making it useful in the manufacture of pharmaceuticals. The efficiency and solubility of this process make it suitable for use as an introduction to other processes involving N-protected amino alcohols or amines., 141699-55-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts