In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 533-73-3, formula is C6H6O3, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. COA of Formula: C6H6O3
Moseev, Timofey D.;Nikiforov, Egor A.;Varaksin, Mikhail V.;Charushin, Valery N.;Chupakhin, Oleg N. research published 《 Metal-Free C-H/C-H Coupling of 2H-Imidazole 1-Oxides with Polyphenols toward Imidazole-Linked Polyphenolic Compounds》, the research content is summarized as follows. The methodol. of nucleophilic substitution of hydrogen (SNH) was successfully applied as a convenient synthetic tool to afford azaheterocyclic derivatives of phenols I [R = 2,4-dihydroxyphenyl, 2,3-dihydroxynaphthalen-1-yl, 2,4,6-trihydroxyphenyl, etc.; R1 = Me, 4-bromophenyl, naphthalen-2-yl, etc.; R2 = Me, Et; R3 = Me; R2R3 = -(CH2)5-] of various architectures. A series of novel imidazole-linked polyphenolic compounds I were first prepared in 72-95% yields through the direct metal-free C-H/C-H polyphenols such as resorcinol, 2,3-naphthalenediol, 1,3,5-benzenetriol, etc. coupling with 2H-imidazole 1-oxides II. Comprehensive studies on the reaction condition optimization, scope, and limitations enabled the development of a straightforward method toward novel bifunctional derivatives bearing both phenolic and imidazole scaffolds I of particular interest in the design of challenging mols. for versatile applications in medicinal chem. and materials science.
533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., COA of Formula: C6H6O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts