《Cyclometalated Ruthenium Pincer Complexes as Catalysts for the α-Alkylation of Ketones with Alcohols》 was published in Chemistry – A European Journal in 2020. These research results belong to Piehl, Patrick; Amuso, Roberta; Alberico, Elisabetta; Junge, Henrik; Gabriele, Bartolo; Neumann, Helfried; Beller, Matthias. Related Products of 100-55-0 The article mentions the following:
Ruthenium PNP pincer complexes bearing supplementary cyclometalated C,N-bound ligands have been prepared and fully characterized for the first time. By replacing CO and H- as ancillary ligands in such complexes, addnl. electronic and steric modifications of this topical class of catalysts are possible. The advantages of the new catalysts are demonstrated in the general α-alkylation of ketones with alcs. following a hydrogen autotransfer protocol. Herein, various aliphatic and benzylic alcs. were applied as green alkylating agents for ketones bearing aromatic, heteroaromatic or aliphatic substituents as well as cyclic ones. Mechanistic investigations revealed that during catalysis, Ru carboxylate complexes are predominantly formed whereas neither the PNP nor the CN ligand are released from the catalyst in significant amounts In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Related Products of 100-55-0)
3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Related Products of 100-55-0
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts