In 1987,Anthoni, Uffe; Nielsen, Per H.; Smith-Hansen, Lene; Wium-Andersen, Soeren; Christophersen, Carsten published 《Charamin, a quaternary ammonium ion antibiotic from the green alga Chara globularis》.Journal of Organic Chemistry published the findings.Application of 18621-18-6 The information in the text is summarized as follows:
The aqueous extract of the green characean alga C. globularis has antibiotic activity against a natural population of bacteria from pond water. The active component, charamin (I), 4-azoniaspiro[3,3]heptan-2,6-diol, was identified by 1H, 13C NMR, and IR spectroscopy. I was synthesized from azetidin-3-ol by reaction with epichlorohyrin. In the experiment, the researchers used Azetidin-3-ol hydrochloride(cas: 18621-18-6Application of 18621-18-6)
Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Application of 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.
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