Synthetic Route of C6H7NOIn 2020 ,《Ruthenium Catalyzed Divergent Alkylation and Olefination of Methyl 1,3,5-Triazines with Alcohols》 was published in European Journal of Organic Chemistry. The article was written by Su, Chengwu; Zeng, Ming; Zhang, Chen; Cui, Dong-Mei. The article contains the following contents:
An efficient ruthenium-catalyzed divergent alkylation and olefination of Me 1,3,5-triazines with alcs. have been developed. The selectivity can be rationally tuned by the judicious choice of ruthenium catalyst, wherein Ru(PPh3)3Cl2 delivers alkylated 1,3,5-triazines and RuCl3 gives olefinated 1,3,5-triazines in up to 98% yield. Following this simple, facile, and high atom economical protocol, a broad range of products was prepared in moderate to good yields and tolerated heterocyclic or benzylic alcs. containing functionalities. The overall transformation operates through dehydrogenation of primary alcs. under the reaction conditions to provide the corresponding aldehydes, which further undergo condensation with Me 1,3,5-triazines. The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0Synthetic Route of C6H7NO)
3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Synthetic Route of C6H7NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts