《Creation of discrete active site domains via mesoporous silica poly(styrene) composite materials for incompatible acid-base cascade reactions》 was written by Cleveland, Jacob W.; Kumar, Dharam Raj; Cho, Jinwon; Jang, Seung Soon; Jones, Christopher W.. Reference of 5-Hexen-1-ol And the article was included in Catalysis Science & Technology in 2021. The article conveys some information:
This work highlights the design and synthesis of bifunctional mesoporous silicate – polymer composite dual acid-base supported cascade catalysts. Compartmentalization of the two incompatible active sites is sought by segregating acid sites on the silica surface, and base sites within polymer chains and/or polymer domains. The ability to isolate and segregate active sites via control of the mesoporous silica pore size and polymer mol. weight is probed with silica samples functionalized by a grafting-to process. Supplemental activator and reducing agent (SARA) atom transfer radical polymerization is used to synthesize random copolymers containing protected primary amines. Thiol-ene ‘click’ chem. facilitates silica functionalization via a convergent approach, with the ene-functionalized polymer end group and silica-grafted thiols forming SBA/MCM-SH-poly(styrene-co-2-(4-vinylbenzyl)isoindoline-1,3-dione). Polymer deprotection and thiol oxidation produces primary amine/sulfonic acid containing composite catalysts. With the polymer supported Lewis base and silica grafted Bronsted acid, the two-step deacetalization – Knoevenagel condensation cascade is explored to assess the ability of these polymer/silica hybrids to segregate active sites, allowing both acid and base site accessibility. Six composite catalysts are synthesized and tested in individual and cascade reactions with kinetic results demonstrating that lower mol. weight SBA-15-P1 and MCM-41-P1 catalysts outperform (higher turnover frequencies and initial rates) their higher mol. weight analogs, as well as a polymer-free system containing mol. active sites dispersed on the silica surface. Higher mol. weight composite catalysts perform more poorly due to limited chain solubility, mass transfer limitations, and poor catalyst accessibility. In many cases, the polymer chains effectively thread into the mesopores, with higher mol. weight polymers leading to pore blockage and inhibited mass transfer. The experimental process involved the reaction of 5-Hexen-1-ol(cas: 821-41-0Reference of 5-Hexen-1-ol)
5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Reference of 5-Hexen-1-ol
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