Alfonzo, Edwin; Hande, Sudhir M. published the artcile< α-Heteroarylation of Thioethers via Photoredox and Weak Bronsted Base Catalysis>, Safety of 2-(Phenylthio)ethanol, the main research area is Heteroarylation thioether photoredox weak Bronsted base catalysis; Classical Minisci Reaction with Thioethers.
We report the C-H activation of thioethers to α-thio alkyl radicals and their addition to N-methoxyheteroarenium salts for the redox-neutral synthesis of α-heteroaromatic thioethers. Studies are consistent with a two-step activation mechanism, where oxidation of thioethers to sulfide radical cations by a photoredox catalyst is followed by α-C-H deprotonation by a weak Bronsted base catalyst to afford α-thio alkyl radicals. Further, N-methoxyheteroarenium salts play addnl. roles as a source of methoxyl radical that contributes to α-thio alkyl radical generation and a sacrificial oxidant that regenerates the photoredox catalytic cycle.
Organic Letters published new progress about Bronsted bases Role: CAT (Catalyst Use), USES (Uses). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts