Shan, Shan; Xiong, Yi; Guo, Jianguo; Liu, Mengyao; Gao, Xin; Fu, Xinjing; Zeng, Deyong; Song, Chen; Zhang, Yingchun; Cheng, Dayodu; Lu, Weihong published the artcile< Effect of an inulin-type fructan from Platycodon grandiflorum on the intestinal microbiota in rats exposed to PM2.5>, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol, the main research area is Platycodon fructan gastroprotectant polysaccharide intestinal microbiota PM25 exposure; Intestinal microbiota; Inulin-type fructan; PM2.5; Platycodon grandiflorum.
In this study, an inulin-type fructan (PGPI-1-a) was isolated from the roots of Platycodon grandiflorum. PGPI-1-a was composed of (2 → 1)-linked β-D-fructofuranose (Fruf) and a terminal α-D-glucopyranose (Glcp) with a mol. weight of 12.1 kDa. PM2.5 exposure has brought a great threat to human health in recent years. Therefore, this study explored the effect of PGPI-1-a on the intestinal microbial community structure of rats exposed to PM2.5 using the animal model of PM2.5 inhalation exposure. The results showed that PGPI-1-a could regulate the intestinal microbiota by partly restoring the perturbed levels of Peptoniphilaceae_[G-2] and Lachnospiraceae_[G-2] caused by PM2.5 exposure. In addition, the relative abundance of Butyrivibrio, a butyric acid-producing genera, significantly increased after PGPI-1-a intervention. These results indicated that PGPI-1-a could improve the imbalance of intestinal microbiota due to PM2.5 exposure to a certain extent.
Carbohydrate Polymers published new progress about Actinobacteria. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts