Maiti, Sudip; Li, Yingzi; Sasmal, Sheuli; Guin, Srimanta; Bhattacharya, Trisha; Lahiri, Goutam Kumar; Paton, Robert S.; Maiti, Debabrata published the artcile< Expanding chemical space by para-C-H arylation of arenes>, Application In Synthesis of 492-62-6, the main research area is biaryl scaffold preparation.
A robust catalytic system that displayed unique efficacy toward para-arylation of highly functionalized substrates such as drug entities, giving access to structurally diversified biaryl scaffolds, e.g., I was developed. This diversification process provided access to an expanded chem. space for further exploration in drug discovery. Further, the applicability of the transformation was realized through the synthesis of drug mols. bearing a biphenyl fragment. Computational and exptl. mechanistic studies further provided insight into the catalytic cycle operative in this versatile C-H arylation protocol.
Nature Communications published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application In Synthesis of 492-62-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts