Davidson, Stuart C.; Gomes, Gabriel dos Passos; Kuhn, Leah R.; Alabugin, Igor V.; Kennedy, Alan R.; Tomkinson, Nicholas C. O. published the artcile< Organocatalytic sulfoxidation>, Safety of 2-(Phenylthio)ethanol, the main research area is sulfide diketone catalyst sulfoxidation kinetics; sulfoxide preparation.
Treatment of a sulfide with a catalytic amount of a 1,3-diketone in the presence of silica sulfuric acid as a co-catalyst and hydrogen peroxide (50% aq) as the stoichiometric oxidant leaded to the corresponding sulfoxide product. The reaction was effective for diaryl, aryl-alkyl and dialkyl sulfides and was tolerant of oxidisable and acid sensitive functional groups. It showed that the tris-peroxide , formed on reaction of pentane-2,4-dione with hydrogen peroxide under acidic reaction conditions, it oxidised two equivalent of sulfide using the exocyclic peroxide groups whereas the endocyclic peroxide remained intact. Calculations provided a mechanism consistent with exptl. observations and suggested the reaction proceeded via an initial acid catalyzed ring opening of a protonated tris-peroxide prior to oxygen transfer to a sulfur nucleophile.
Tetrahedron published new progress about Peroxides Role: RGT (Reagent), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts