Month: November 2022

《Color-tunable ultralong organic phosphorescence upon temperature stimulus》 was written by Niu, Zuoji; Ma, Chaoqun; Ye, Wenpeng; Wang, He; Jia, Wenyong; Shi, Huixian; Shi, Huifang; An, Zhongfu; Huang, Wei. Electric Literature of C3H7BrOThis research focused onultralong organic phosphorescence temperature stimulus photophys property. The article conveys some information:

A new class of single-component mol. crystal with color-tunable ultralong organic phosphorescence (UOP) was designed and synthesized through alkyl chain engineering. Forming a more rigid environment at 77 K, the color-tunable UOP from yellow-white to blue-green is achieved through dual-emission of crystal and amorphous states. In the experimental materials used by the author, we found 3-Bromopropan-1-ol(cas: 627-18-9Electric Literature of C3H7BrO)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Electric Literature of C3H7BrO

Referemce:
Alcohol – Wikipedia,
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《Reversible and Tunable Photoswitching of Protein Function through Genetic Encoding of Azobenzene Amino Acids in Mammalian Cells》 was published in ChemBioChem in 2018. These research results belong to Luo, Ji; Samanta, Subhas; Convertino, Marino; Dokholyan, Nikolay V.; Deiters, Alexander. SDS of cas: 1123172-89-3 The article mentions the following:

The genetic encoding of three different azobenzene phenylalanines with different photochem. properties was achieved in human cells by using an engineered pyrrolysyl tRNA/tRNA synthetase pair. In order to demonstrate reversible light control of protein function, azobenzenes were site-specifically introduced into firefly luciferase. Computational strategies were applied to guide the selection of potential photoswitchable sites that lead to a reversibly controlled luciferase enzyme. In addition, the new azobenzene analogs provide enhanced thermal stability, high photoconversion, and responsiveness to visible light. These small-mol. photoswitches can reversibly photocontrol protein function with excellent spatiotemporal resolution, and preferred sites for incorporation can be computationally determined, thus providing a new tool for investigating biol. processes. The experimental process involved the reaction of (3,5-Difluoro-4-nitrophenyl)methanol(cas: 1123172-89-3SDS of cas: 1123172-89-3)

(3,5-Difluoro-4-nitrophenyl)methanol(cas: 1123172-89-3) belongs to nitro compounds. Nitro compounds have very different half-wave potentials. They depend on the type, number and position of the substituents and rise.SDS of cas: 1123172-89-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2011,Shi, Ying; Zhang, Ya-ran; Di, Hui-feng; Jia, Ming; Zhang, Zhi-bao published 《Synthesis of 3-mercapto-1-(1,3-thiazolin-2-yl)azetidine hydrochloride》.Huaxue Shiji published the findings.Category: alcohols-buliding-blocks The information in the text is summarized as follows:

3-Mercapto-1-(1,3-thiazolin-2-yl) azetidine hydrochloride has been synthesized from 2-mercaptothiazoline, through methylation, SN2 nucleophilic substitution with 3-hydroxyazetidine hydrochloride, activation of the hydroxyl group with methanesulfonyl chloride, SN2 nucleophilic substitution of the resultant mesylate with potassium thioacetate, and basic hydrolysis. The total yield was 51.6%, and purity of product was 98.5%. The method features mild conditions, easy manipulation, high purity and suitability for industrialization.Azetidin-3-ol hydrochloride(cas: 18621-18-6Category: alcohols-buliding-blocks) was used in this study.

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Category: alcohols-buliding-blocks Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2016,Huang, Wei; Zhu, Shou-cheng; Chu, Wei-fa; Yang, Hong-xing; Liang, Hui-hui published 《Synergistic compound and anti-corrosion research of α-amylase in textile industry》.Yinran Zhuji published the findings.SDS of cas: 6381-59-5 The information in the text is summarized as follows:

In order to improve α-amylase desizing effect and prolong the preservation time in textile industry, the desizing technol. for cotton fabric with α-amylase was investigated. The effect of optimum temperature, the optimum pH and enzyme concentration on the desizing effect were discussed. Taking the desizing rate as index, the influences of Na+, K+, Ca2+ inorganic compounds and non-ionic, amphoteric surfactants on desizing effect were studied. In addition, the α-amylase enzyme activity was measured, anti-corrosion effect of different kinds preservatives to α-amylase were investigated. The results show ed that sodium nitrate and potassium nitrate had certain activation of α-amylase; appropriate concentration of non-ionic surfactant and amphoteric surfactant could improve the enzyme desizing effect; 1% Et p-hydroxybenzoate could make the α-amylase remain 92%, 85% and 79% of enzymic activity under 30 °C of preservation for 30 days, 60 days and 90 days, resp. In the experiment, the researchers used Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5SDS of cas: 6381-59-5)

Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5) is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient. SDS of cas: 6381-59-5 It may be used as a constituent to prepare DNS (3,5- dinitrosalicylic acid) reagent and Fehling′s solution B, which are used in the determination of reducing sugar.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Polyhedron included an article by Abbas, Ghulam; Ibrahim, Masooma; Schmidt, Sebastian F. M.; Moreno-Pineda, Eufemio; Anson, Christopher E.; Powell, Annie K.. Recommanded Product: 534-03-2. The article was titled 《Synthesis of five isostructural tetranuclear Fe2Ln2 (Ln = Gd, Tb, Dy, Ho, Er) complexes with an “”inverse butterfly”” core》. The information in the text is summarized as follows:

A 1-pot synthesis leading to in situ ligand formation enabled the preparation of five isostructural tetranuclear Fe2Ln2 coordination clusters [Fe2Ln2(μ4L)2(mpm)2(piv)2(N3)3.5(Cl)0.5], where H2L is 2-((pyridin-2-ylmethylene)amino)propan-1,3-diol, Hmpm is methoxy(2-pyridinyl)methanol, piv is pivalate and Ln = Gd (1), Tb (2), Dy (3), Ho (4), Er (5). These show an unprecedented core structure. The coordination compounds were fully characterized by IR spectroscopy, elemental anal., powder x-ray diffraction and single crystal X-ray diffraction. Magnetic measurements indicate intramol. antiferromagnetic and ferromagnetic interactions. The finding is important in developing synthetic strategies for the preparation of new mol. based magnetic materials. The experimental part of the paper was very detailed, including the reaction process of 2-Aminopropane-1,3-diol(cas: 534-03-2Recommanded Product: 534-03-2)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Recommanded Product: 534-03-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Lemon juice as an efficient biocatalyst for one pot three component green synthesis of substituted 5-amino-1-(2,4-dinitrophenyl)-1h-pyrazole-4-carbonitriles》 was published in Chemica Sinica in 2020. These research results belong to Suman, S.; Singh, Rajvir; Gulati, Susheel; Suprita. Safety of 3-Hydroxybenzaldehyde The article mentions the following:

An eco-friendly one pot three component green synthesis of substituted 5-amino-1-(2,4-dinitrophenyl)-1H-pyrazole-4-carbonitriles I (R1 = H, Cl, OH; R2 = H, OH, NO2; R3 = H, Cl, Me, OMe, OH) have been carried out in presence of lemon juice as a recyclable catalyst. The use of biocatalysts is focused on eco-friendly organic synthesis. Here, lemon juice, which is an inexpensive, safe and eco-friendly catalyst in the one pot three components reaction of aryl aldehydes 2-R1-3-R2-4-R3-C6H2CHO, malononitrile and 2,4-dinitrophenyl hydrazine for the synthesis of pyrazole derivatives I under mild conditions have been showed. After optimization of reaction conditions for synthesis of pyrazoles I (R1 = R2 = H; R3 = OMe), it was found that 4.0mL of lemon juice gave 82% yield in 1.4 h at room temperature in solvent-free conditions. This novel and eco-friendly pathway has the merits of high yield, simple handling and benign synthesis. In addition to this study using 3-Hydroxybenzaldehyde, there are many other studies that have used 3-Hydroxybenzaldehyde(cas: 100-83-4Safety of 3-Hydroxybenzaldehyde) was used in this study.

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Safety of 3-Hydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Palladium-Catalyzed Desulfurative Amide Formation from Thioureas and Arylboronic Acids》 was published in ChemCatChem in 2020. These research results belong to Su, Jianke; Li, Wendong; Li, Xin; Xu, Jian; Song, Qiuling. Formula: C12H17BO2 The article mentions the following:

Herein, the Pd-catalyzed desulfurative amide formation involved Suzuki-Miyaura coupling reaction, notably the Pd complex was generated in situ from thioureas and Ag salt and Pd catalyst were discovered. Silver salt was essential for the construction of this type of carbenes from available and stable thioureas R1R2NC(S)NR3R4 (R1 = Me, 4-fluorophenyl, 4-chlorophenyl, phenyl; R2 = Me; R3 = Me; R4 = Me, 4-fluorophenyl, 4-chlorophenyl, phenyl; R1R2 = -(CH2)5-, -(CH2)4-, -(CH2)2O(CH2)2-; R3R4 = -(CH2)5-, -(CH2)4-, -(CH2)2O(CH2)2-) and well participated in the catalytic cycle. A method for the synthesis of arylamides R5C(O)NR3R4 (R5 = acetyl, Ph, naphthalen-2-yl, 4-(benzenesulfonyl)morpholine, etc.) from arylboronic acids R5B(OH)2, which greatly enriched the application of thioureas chem. and expanded the application of the Suzuki-Miyaura coupling was developed. The experimental process involved the reaction of 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane(cas: 24388-23-6Formula: C12H17BO2)

4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane(cas: 24388-23-6) can be used as a substrate in the study of Suzuki–Miyaura coupling of various aryl iodides over SiliaCat Pd(0).Formula: C12H17BO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Antitumor activity of new olivacine derivatives》 was published in Molecules in 2020. These research results belong to Piasny, Janusz; Wiatrak, Benita; Dobosz, Agnieszka; Tylinska, Beata; Gebarowski, Tomasz. HPLC of Formula: 534-03-2 The article mentions the following:

Olivacine is an alkaloid-containing pyridocarbazole structure. It is isolated from the bark of the evergreen timber tree, Aspidosperma olivaceum. Its well-documented anticancer activity led to the synthesis of new derivatives, which are semisynthetic and fully synthetic pyridocarbazoles. This study aimed to evaluate the potential antineoplastic activity of four newly synthesized olivacine derivatives Multidrug resistance is a common phenomenon causing failure in the chemotherapy of many tumors. It is mainly related to increased function of P-glycoprotein, an efflux pump removing cytostatic out of the cells. The cell lines used in the study were colorectal carcinoma cell lines: LoVo (doxorubicin-sensitive) and LoVo/DX (doxorubicin-resistant). The NHDF cell line was used to assess cell viability. First, the cells were incubated with olivacine derivatives In the next step, the following assays were performed: DCF-DA assay, MTT assay, rhodamine 123 assay, detection of apoptosis, proliferation inhibition-mitotic index. The tested compounds showed higher antineoplastic potential and lower toxicity than the reference compound ellipticine. The results indicate that the new olivacine derivatives are good candidates for future anticancer drugs. In addition to this study using 2-Aminopropane-1,3-diol, there are many other studies that have used 2-Aminopropane-1,3-diol(cas: 534-03-2HPLC of Formula: 534-03-2) was used in this study.

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.HPLC of Formula: 534-03-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Beta-cyclodextrin decorated CdS nanocrystals boosting photocatalytic conversion of alcohols》 was published in CCS Chemistry in 2020. These research results belong to Wang, Juan; Feng, You-Xiang; Zhang, Min; Zhang, Chao; Li, Ming; Li, Sheng-Jie; Zhang, Wen; Lu, Tong-Bu. Related Products of 100-55-0 The article mentions the following:

Regarding the utilization of semiconductor nanocrystals (NCs) in photocatalysis, the significant challenge is to eliminate the hindrance of decorated surface ligands on the photocarrier transport while maintaining their overall stability. Herein, we report a novel and stable catalyst comprising CdS NCs and surfacebound mono-(6-mercapto-6-deoxy)-β-cyclodextrin (HS-β-CD) mols. (denoted as CdS-CD), which could convert alcs. selectively into diols or aldehydes and H2 under visible light irradiation, with 100% atom utilization, using an aqueous medium as a green solvent. The decorated β-CD ligands did not only confer a good stability of CdS-CD in water but also showed a high host-guest affinity to the alc. species, thereby, guaranteeing a close vicinity of alc. mols. at the surface of CdS NCs and minimizing the hindrance of surface ligands on the photocarrier transport. As a result, the CdS-CD displayed much improved photocatalytic activity for the conversion of alcs. in aqueous media, compared with those of CdS-BF4 NCs. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Related Products of 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Related Products of 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Benchtop NMR for Online Reaction Monitoring of the Biocatalytic Synthesis of Aromatic Amino Alcohols》 was published in ChemCatChem in 2020. These research results belong to Claassen, C.; Mack, K.; Rother, D.. Recommanded Product: 3-Hydroxybenzaldehyde The article mentions the following:

Online analytics provides insights into the progress of an ongoing reaction without the need for extensive sampling and offline anal. In this study, we investigated benchtop NMR as an online reaction monitoring tool for complex enzyme cascade reactions. Online NMR was used to monitor a two-step cascade beginning with an aromatic aldehyde and leading to an aromatic amino alc. as the final product, applying two different enzymes and a variety of co-substrates and intermediates. Benchtop NMR enabled the concentration of the reaction components to be detected in buffered systems in the single-digit mM range without using deuterated solvent. The concentrations determined via NMR were correlated with offline samples analyzed via uHPLC and displayed a good correlation between the two methods. In summary, benchtop NMR proved to be a sensitive, selective and reliable method for online reaction monitoring in (multi-step) biosynthesis. In future, online analytic systems such as the benchtop NMR devices described might not only enable direct monitoring of the reaction, but may also form the basis for self-regulation in biocatalytic reactions. The experimental process involved the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Recommanded Product: 3-Hydroxybenzaldehyde)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Recommanded Product: 3-Hydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts