Tag: M.W=100-150

Yu, Haiyan; Xie, Tong; Xie, Jingru; Ai, Lianzhong; Tian, Huaixiang published the artcile< Characterization of key aroma compounds in Chinese rice wine using gas chromatography-mass spectrometry and gas chromatography-olfactometry>, Application In Synthesis of 104-76-7, the main research area is Chinese rice wine aroma compounds GC MS olfactometry; Chinese rice wine; Gas chromatography–mass spectrometry; Gas chromatography–olfactometry; Key aroma compounds; Partial least squares regression.

To determine the key aroma compounds in Chinese rice wine (CRW), four types of CRW (YH, JF, SN, and XX) were analyzed by gas chromatog.-mass spectrometry (GC-MS), gas chromatog.-olfactometry (GC-O), and sensory evaluation. The contributions of the key aroma compounds to the flavor characteristics were determined by partial least squares regression. Sixty-one aroma compounds were detected. Twenty-five components were identified as odor-active compounds On the basis of their odor active values, 18 odor-active compounds were determined as key aroma compounds Et isovalerate, Et butyrate, Et acetate, Et hexanoate, and phenylethyl alc. were key aroma compounds in all four types of wine. The unique key aroma compounds of JF wine were isovaleraldehyde and isoamyl acetate; those of XX wine were 1-butanol, benzaldehyde, Et benzoate, Et phenylacetate, 2-octanone, and furfural; that of YH wine was Et 2-methylbutyrate; and those of SN wine were 1-butanol, 1-hexanol, 2-butenoic acid Et ester, and 3-methyl-1-butanol.

Food Chemistry published new progress about Gas chromatography (combined with olfactometry). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Application In Synthesis of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Clive, Derrick L. J.; Peng, Jianbiao; Fletcher, Stephen P.; Ziffle, Vincent E.; Wingert, David published the artcile< Synthesis of Diverse 2,3-Dihydroindoles, 1,2,3,4-Tetrahydroquinolines, and Benzo-Fused Azepines by Formal Radical Cyclization onto Aromatic Rings>, HPLC of Formula: 6850-39-1, the main research area is dihydroindole preparation; quinoline benzotetrahydro stereoselective preparation; tetrahydrobenzoazepine preparation; iodophenol chiral amino alc coupling; aryl amino alc stereoselective preparation N protection; hydroxyalkylhydroxyphenyl carbamate stereoselective preparation iodination; hydroxyphenyliodoalkyl carbamate stereoselective preparation oxidation; iodoalkylcyclohexadienyl carbamate stereoselective preparation radical cyclization; hexahydroindole carbamate preparation rearomatization; hexahydroquinoline carbamate stereoselective preparation rearomatization; carbamate hexahydroindole stereoselective preparation Grignard.

2,3-Dihydroindoles, 1,2,3,4-tetrahydroquinolines, e.g., I, and 2,3,4,5-tetrahydrobenzo[b]azepines are available by a process that represents formal radical cyclization onto aromatic rings. Optically pure benzo-fused heterocycles are also accessible by this method. P-Iodophenols, especially those with the phenolic oxygen protected as a MOM-ether, can be coupled with amino alcs. to produce N-aryl amino alcs., which can be converted into the corresponding alkyl iodides in which the nitrogen is protected as a carbamate. These compounds give cross-conjugated ketones after removal of the phenolic protecting group and oxidation with PhI(OAc)2 in the presence of MeOH. The ketones undergo 5-, 6- or 7-exo-trigonal radical cyclization, and then exposure to acid, or sequential treatment with a Grignard reagent and then acid, effects rearomatization to produce the benzo-fused nitrogen heterocycles.

Journal of Organic Chemistry published new progress about Aromatization. 6850-39-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H13NO, HPLC of Formula: 6850-39-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Miyazaki, Kanako; Nakata, Kenya published the artcile< Two-Step Kinetic Resolution of Racemic Secondary Benzylic Alcohols Using the Combination of Enantioselective Silylation and Acylation: One-Pot Procedure Catalyzed by Chiral Guanidine>, Synthetic Route of 403-41-8, the main research area is alc benzylic enantioselective preparation kinetic resolution; ester preparation enantioselective kinetic resolution benzylic alc; benzylic alc chiral guanidine catalyst silylation acylation kinetic resolution.

A novel two-step kinetic resolution of racemic secondary benzylic alcs. with practical enantiomeric ratios was achieved. The reactions were carried out via a one-pot operation by combining enantioselective silylation and acylation mediated by the same chiral guanidine catalyst.

Journal of Organic Chemistry published new progress about Acylation catalysts (stereoselective). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Garlatti, Laura; Huet, Raphael; Alvarez, Karine published the artcile< Efficient access to 3'-deoxy-3'-(4-substituted-1,2,3-triazol-1-yl)-thymidine derivatives via ligand-promoted CuAAC>, Computed Properties of 10602-04-7, the main research area is click alkyne azide triazole cycloaddition catalyst preparation nucleoside.

Herein we describe an efficient and rapid access to 3′-deoxy-3′-(4-substituted-1,2,3-triazol-1-yl)-thymidine derivatives, e.g. I, using 1,3-dipolar cycloaddition reaction catalyzed by copper(I). Innovative conditions allow us to generate target compounds in a one-pot reaction mixing 3′-azido-3′-deoxythymidine, alkyne, copper sulfate pentahydrate, sodium ascorbate and tris(benzyltriazolylmethyl)amine in a water:tert-butanol solvent mixture Rapid treatment of the reaction and subsequent flash purification chromatog. afforded pure compounds in an overall yield of 71-100%. All eleven synthesized compounds were identified on the basis of their spectral data anal. (1H, 13C, 2D NMR and high-resolution mass spectra).

Tetrahedron published new progress about 1,3-Dipolar cycloaddition reaction. 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Computed Properties of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bierwirth, S. Peter; Honorio, Gabriel; Gainaru, Catalin; Boehmer, Roland published the artcile< Linear and nonlinear shear studies reveal supramolecular responses in supercooled monohydroxy alcohols with faint dielectric signatures>, Category: alcohols-buliding-blocks, the main research area is supercooled monohydroxy alc dielec loss.

Monohydroxy alcs. (MAs) with Me and hydroxyl side groups attached to the same carbon atom in the alkyl backbone can display very weak structural and supramol. dielec. relaxation processes when probed in the regime of small elec. fields. This can render their separation and assignment difficult in the pure liquids When mixing with bromoalkanes, a faint Debye-like process can be resolved dielec. for 4-methyl-4-heptanol. To achieve a separation of structural and supramol. processes in pure 4-methyl-4-heptanol and 3-methyl-3-heptanol, mech. experiments are carried out in the linear-response regime as well as using medium-angle oscillatory shear amplitudes. It is demonstrated that first-order and third-order nonlinear mech. effects allow for a clear identification of supramol. viscoelastic modes even for alcs. in which they leave only a weak signature in the linear-response shear modulus. Addnl., the nonlinear rheol. behavior of 2-ethyl-1-hexanol is studied, revealing that its linearly detected terminal mode does not coincide with that revealed beyond the linear-response regime. This finding contrasts with those for the other MAs studied in this work. (c) 2019 American Institute of Physics.

Journal of Chemical Physics published new progress about Dielectric loss. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Wenzhong; Wan, Baibai; Shi, Ran; Chen, Si; Li, Jiazhu; Wang, Fangzhen; Niu, Hexu; Xu, Xin-Ming; Wang, Wei-Li published the artcile< Catalyst-free one-pot cascade cyclization: An efficient synthesis of isoindolobenzoxazinones and isoindoloquinazolinones derivatives>, Category: alcohols-buliding-blocks, the main research area is isoindolobenzoxazinone isoindoloquinazolinone preparation one pot catalyst free; acylbenzoic acid amino alc diamine cascade cyclization.

A practical and efficient catalyst-free cascade cyclization reaction of 2-acylbenzoic acids with various amino alcs. or diamines was developed. This protocol provides a powerful and straightforward method for the one-pot synthesis of diverse isoindolobenzoxazinones, isoindoloquinazolinones and their derivatives The synthetic strategy evades the use of catalyst, shows a broad substrate scope and could be performed in gram-scale.

Tetrahedron published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Monsen, Paige J.; Luzzio, Frederick A. published the artcile< Applicability of aluminum amalgam to the reduction of arylnitro groups>, COA of Formula: C7H9NO, the main research area is aryl amine preparation; arylnitro compound reduction; Aluminum amalgam; Arylnitro groups; Azides; Click chemistry; Reduction.

An array of arylnitro compounds RNO2 [R = 4-methylphenyl, naphthalen-1-yl, (morpholin-4-yl)carbonyl, etc.] with various functionality was treated with freshly-prepared aluminum amalgam in THF/water solution and resulted in the corresponding arylamines RNH2. The Al(Hg)-mediated reductions are relatively rapid with consumption of the amalgam and disappearance of starting material occurring over 20-30 min. The workup of the reductions involves only removal of the insoluble byproducts by filtration followed by concentration Only in some cases is chromatog. required to secure the pure product. The desired arylamines are furnished in quantities of 25-100 mg, which in some cases, could be taken on to the next reaction without further purification Reductions of 4-nitrobenzyl derivatives of carbohydrates or nucleosides, e.g., I were selective in affording the corresponding 4-aminobenzyl products. To show applicability in click chem., selected aminobenzyl products are directly azidated to yield products that were then used in click reactions to afford the corresponding 1,2,3-triazoles, e.g., II.

Tetrahedron Letters published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, COA of Formula: C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sivakumar, Ganesan; Subaramanian, Murugan; Balaraman, Ekambaram published the artcile< Single-Molecular Mn(I)-Complex-Catalyzed Tandem DoubleDehydrogenative Cross-Coupling of (Amino)Alcohols under Solventless Conditions with the Liberation of H2 and H2O>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is quinoline pyridine preparation green; primary amino alc double dehydrogenative cross coupling manganese.

Sustainable chem. production requires fundamentally new types of catalysts and catalytic technologies. The development of coherent and robust catalytic systems based on earth-abundant transition metals is essential but extremely challenging. Herein, authors report the first report on a single Mn(I)-PNP catalyzed tandem C-C and C-N bond formation via double dehydrogenative coupling of amino alcs. with primary alcs. The current method covers a wide range of substrates, including aryl, aliphatic acyclic, and cyclic primary alcs., as well as amino alcs., to provide diverse N-heterocyclic compounds (pyridine and quinoline derivatives) in good to excellent yields (50 examples). The reaction proceeds under benign, solventless conditions with the liberation of mol. hydrogen and water as the only byproducts. Various control and labeling experiments and kinetic, NMR, and mechanistic studies suggest that the reaction operates via the acceptorless double dehydrogenative coupling pathway, selectively assimilating to provide desired N-heterocycles. Several selective bond activation/formation reactions occur sequentially via amine-amide metal-ligand cooperation.

ACS Sustainable Chemistry & Engineering published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hoong, Seng Soi; Arniza, Mohd. Zan; Mariam, Nek Mat Din Nik Siti; Armylisas, Abu Hassan Noor; Yeong, Shoot Kian published the artcile< Synthesis and physicochemical properties of novel lauric acid capped estolide esters and amides made from oleic acid and their evaluations for biolubricant basestock>, Application In Synthesis of 104-76-7, the main research area is oleic lauric acid estolide ester amide biolubricant oxidative stability.

Vegetable oils have been used as environmentally friendly biolubricants because of their inherent biodegradability, good lubricity, higher viscosity index and low evaporative loss. However, their use is limited due to significantly poor cold flow properties and inferior oxidative stability. This paper presents an approach to modify vegetable oil derivatives namely oleic acid to yield biolubricant with good cold flow properties and oxidation stability. Oleic acid was converted to polyhydroxy estolide through reaction with only hydrogen peroxide, which is considered a ‘green’ oxidant. The synthesized polyhydroxy estolide was further reacted with appropriate amount of lauric acid to end-cap its hydroxy groups, which yielded lauric acid capped estolide as the product. Subsequently, the prepared lauric acid capped estolide was reacted with branched and straight chain alcs. as well as secondary amines to afford estolide esters and amides. In general, most of the prepared samples showed improved cold flow properties as compared to vegetable oil-based lubricants, where the best pour point (-41°C) was achieved by 4-methyl-2-pentyl estolide ester. Meanwhile, estolide amides exhibited the best oxidative stability among samples evaluated with an oxidation onset temperature of 205°C, which is significantly higher than vegetable oil-based lubricants. Generally, the oxidative stability, viscosity index and anti-wear properties of prepared estolide esters and amides were found to be comparable to the properties of com. samples used as benchmark.

Industrial Crops and Products published new progress about Acid number. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Application In Synthesis of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dong, Shihua; Jia, Bing; Chen, Xiubin; Jiang, Xiaobo published the artcile< Liquid-Liquid Equilibrium for Ternary System of Water + 2-Methyl-3-buten-2-ol + (Methyl tert-butyl ether/Butyl acetate/4-Methyl-2-pentanone/2-Ethyl-1-hexanol) at 308.2 K>, Safety of 2-Ethylhexan-1-ol, the main research area is water methylbutenol methyltertbutylether butyl acetate methylpentanone ethylhexanol ternary system; ternary system liquid equilibrium.

For separation of the azeotropes of water + 2-methyl-3-buten-2-ol by liquid-liquid extraction, Me tert-Bu ether or Bu acetate or 4-methyl-2-pentanone or 2-ethyl-1-hexanol was selected as the extraction solvent. The liquid-liquid equilibrium (LLE) data for water + 2-methyl-3-buten-2-ol + (Me tert-Bu ether/butyl acetate/4-methyl-2-pentanone/2-ethyl-1-hexanol) ternary systems at 308.2 K under 101.3 kPa were determined The distribution coefficient and the separation factor were calculated to evaluate the extraction ability of different solvents. The Othmer-Tobias, Bachman, and Hand equations were applied to verify the reliability of the exptl. LLE data. Meanwhile, the exptl. LLE data were successfully correlated by the NRTL and UNIQUAC models with the root-mean-square deviations (RMSD) were less than 0.42%.

Journal of Solution Chemistry published new progress about Extraction. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Safety of 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts