Tag: M.W=100-150

Meng, Genyi; Guo, Taijie; Ma, Tiancheng; Zhang, Jiong; Shen, Yucheng; Sharpless, Karl Barry; Dong, Jiajia published the artcile< Modular click chemistry libraries for functional screens using a diazotizing reagent>, SDS of cas: 6850-39-1, the main research area is alkyl aryl azide triazole chemoselective preparation; fluorosulfonyl azide generation chemoselective diazotization primary amine; combinatorial generation library alkyl aryl azide cycloaddition alkyne; functional screen click chem azide generated in situ.

Alkyl and aryl azides were prepared from the corresponding primary alkyl and aryl amines by reaction with fluorosulfonyl azide generated in situ from a fluorosulfonylimidazolium triflate and sodium azide, expanding access to azides and both to the 1,2,3-triazoles derived from them and to functional screens employing them. The method allowed the preparation of a library of >1000 azides from the corresponding amines; the azide library underwent copper-catalyzed azide-alkyne cycloaddition reactions to yield a library of >1000 1,2,3-triazoles.

Nature (London, United Kingdom) published new progress about Alkyl azides Role: CMB (Combinatorial Study), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 6850-39-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H13NO, SDS of cas: 6850-39-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qiu, Qianfeng; Yang, Sirun; Gerkman, Mihael A.; Fu, Heyifei; Aprahamian, Ivan; Han, Grace G. D. published the artcile< Photon Energy Storage in Strained Cyclic Hydrazones: Emerging Molecular Solar Thermal Energy Storage Compounds>, Computed Properties of 104-76-7, the main research area is photon energy storage strained cyclic hydrazones; mol solar thermal energy storage compound.

The generally small Gibbs free energy difference between the Z and E isomers of hydrazone photoswitches has so far precluded their use in photon energy storing applications. Here, we report on a series of cyclic and acyclic hydrazones, which possess varied degrees of ring strain and, hence, stability of E isomers. The photoinduced isomerization and concurrent phase transition of the cyclic hydrazones from a crystalline to a liquid phase result in the storage of a large quantity of energy, comparable to that of azobenzene derivatives We demonstrate that the macrocyclic photochrome design in combination with phase transition is a promising strategy for mol. solar thermal energy storage applications.

Journal of the American Chemical Society published new progress about Energy storage (solar). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Computed Properties of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Umeyama, Tomokazu; Igarashi, Kensho; Sasada, Daiki; Ishida, Keiichi; Koganezawa, Tomoyuki; Ohtani, Shunsuke; Tanaka, Kazuo; Imahori, Hiroshi published the artcile< Efficient Exciton Diffusion in Micrometer-Sized Domains of Nanographene-Based Nonfullerene Acceptors with Long Exciton Lifetimes in Blend Films with Conjugated Polymer>, Name: 2-Ethylhexan-1-ol, the main research area is exciton diffusion nanographene nonfullerene acceptor blend film conjugated polymer; exciton diffusion; nonfullerene acceptors; organic photovoltaics; phase separation; side chain; singlet exciton lifetime; thienoazacoronene.

Phase-separated structures in photoactive layers composed of electron donors and acceptors in organic photovoltaics (OPVs) generally exert a profound impact on the device performance. Nonfullerene acceptors (NFAs) where a heteronanographene central core was furnished with branched alkoxy chains of different lengths, TACIC-EH, TACIC-BO, and TACIC-HD, were prepared to adjust the aggregation tendency and systematically probe the relations of film structures with photophys. and photovoltaic properties. The side-chain length showed negligible effects on the absorption properties and energy levels of TACICs. Regardless of the chain length, all TACIC films exhibited characteristically long singlet exciton lifetimes (1330-2330 ps) compared to those in solution (≤220 ps). Using a conjugated polymer donor, PBDB-T, the best OPV performance was achieved with TACIC-BO that contained medium-length chains, exhibiting a power conversion efficiency (PCE) of 9.92%. TACIC-HD with the longest chains showed deteriorated electron mobility due to the long insulating alkoxy groups. The PBDB-T:TACIC-HD-based device revealed a low charge collection efficiency and PCE (8.21%) relative to the PBDB-T:TACIC-BO-based device, but their film morphols. were analogous. TACIC-EH with the shortest chains showed low solubility and formed μm-sized large aggregates in the blend film with PBDB-T. Although the charge collection efficiency of PBDB-T:TACIC-EH was lower than that of PBDB-T:TACIC-BO, the efficiencies of exciton diffusion to the donor-acceptor interface were sufficiently high (>98%) owing to the elongated singlet exciton lifetime of TACIC-EH. The PCE of the PBDB-T:TACIC-EH-based device remained moderate (7.10%). Therefore, TACICs with the long singlet exciton lifetimes in the films provide a clear guideline for NFAs with low sensitivity of OPV device performance to the blend film structures, which is advantageous for large-scale OPV production with high reproducibility.

ACS Applied Materials & Interfaces published new progress about Atomic force microscopy. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Name: 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nallagangula, Madhu; Sujatha, Chandragiri; Bhat, Venugopal T.; Namitharan, Kayambu published the artcile< A nanoscale iron catalyst for heterogeneous direct N- and C-alkylations of anilines and ketones using alcohols under hydrogen autotransfer conditions>, Synthetic Route of 5344-90-1, the main research area is aryl amine preparation; alc amine alkylation iron catalyst; preparation aryl ketone; acetophenone alc alkylation iron catalyst; quinoline preparation; amino benzyl alc Friedlander iron catalyst.

An efficient synthesis of amine and ketone derivatives RCH2NHR1 [R = n-pentyl, Ph, 4-OMe, etc.; R1 = Ph, 2-MeOC6H4, 2-pyridyl etc.] and R2CH2CH2C(O)R3 [R2 = Ph, 2-MeC6H4, 4-MeSC6H4, etc.; R3 = Ph, 4-MeC6H4, 4-EtOC6H4, etc.] was described via heterogeneous iron catalyzed direct N- and C-alkylation reactions of amines and acetophenones with alcs. under hydrogen autotransfer conditions. In addition, modified Friedlander synthesis of quinolines I [R4 = H, Me; R5 = Ph, 4-EtC6H4, 4-FC6H4, etc.] was demonstrated from 2-amino benzyl alcs. and acetophenones. A hydrogen autotransfer mechanism was found to operate in these reactions by deuterium labeling studies.

Chemical Communications (Cambridge, United Kingdom) published new progress about Alkylation. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Traeger, Hanna; Ghielmetti, Alyssa; Sagara, Yoshimitsu; Schrettl, Stephen; Weder, Christoph published the artcile< Supramolecular Rings as Building Blocks for Stimuli-Responsive Materials>, Computed Properties of 10602-04-7, the main research area is stimuli responsive material supramol ring; benzothiadiazole; chromogenic; fluorescence; luminescence; naphthalene diimide; quenching; stimuli-responsive polymers.

Stimuli-responsive polymers are of great interest due to their ability to translate changing environmental conditions into responses in defined materials. One possibility to impart such behavior is the incorporation of optically active mols. into a polymer host. Here, we describe how sensor mols. that consist of a π-extended benzothiadiazole emitter and a naphthalene diimide quencher can be exploited in this context. The two optically active entities were connected via different spacers and, thanks to attractive intramol. interactions between them, the new sensor mols. assembled into cyclic structures in which the fluorescence was quenched by up to 43% when compared to solutions of the individual dyes. Detailed spectroscopic investigations of the sensor mols. in solution show that the extent of donor/acceptor interactions is influenced by various factors, including solvent polarity and ion concentration The new sensor mol. was covalently incorporated into a polyurethane; the investigation of the optical characteristics in both the solid and solvent-swollen states indicates that a stimulus-induced formation of associated dye pairs is possible in polymeric materials. Indeed, a solvatochromic quenching effect similar to the behavior in solution was observed for solvent-swollen polymer samples, leading to an effective change of the green emission color of the dye to a yellow color.

Gels published new progress about Differential scanning calorimetry. 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Computed Properties of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Xiangchao; Ai, Yao; Wang, Rongzhou; Liu, Liping; Yang, Jiazhi; Li, Feng published the artcile< Ruthenium-catalyzed acceptorless dehydrogenative coupling of o-aminobenzyl alcohols with ketones to quinolines in the presence of carbonate salt>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is quinoline preparation green chem; aminobenzyl alc ketone acceptorless dehydrogenative coupling ruthenium catalyst.

A ruthenium complex bearing a functional 2,2′-bibenzimidazole ligand [(p-cymene)Ru(BiBzImH2)Cl][Cl] was designed, synthesized and found to be a general and highly efficient catalyst for the synthesis of quinolines I [R = H, Cl, Br; R1 = H, F, Cl, Me, OMe; R2 = t-Bu, cyclopropyl, Ph, pyrazin-2-yl, etc.; R3 = H, Me, Et] and 5,6-dihydrobenzo[c]acridine via acceptorless dehydrogenative coupling of o-aminobenzyl alcs. 2-NH2-4-R-5-R1-C6H2CH2OH with ketones R2C(O)CH2R3 and 1-tetralone in the presence of carbonate salt. It was confirmed that NH units in the ligand are crucial for catalytic activity. The application of this catalytic system for the scale-gram synthesis of biol. active mol. was also undertaken. Notably, this research exhibits new potential of metal-ligand bifunctional catalysts for acceptorless dehydrogenative reactions.

Journal of Catalysis published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Angulo, Beatriz; Fraile, Jose M.; Gil, Laura; Herrerias, Clara I. published the artcile< Comparison of Chemical and Enzymatic Methods for the Transesterification of Waste Fish Oil Fatty Ethyl Esters with Different Alcohols>, Category: alcohols-buliding-blocks, the main research area is enzyme transesterification waste fish oil fatty ethyl ester alc.

Fatty acid esters of 2-ethyl-1-hexanol (EH), 2-hexyl-1-decanol (HD), and isopropanol have been obtained from a mixture of Et esters obtained as a fish oil byproduct. Homogeneous base catalysis with alk. hydroxides and alkoxides has been compared with the use of two com. available immobilized lipases. The enzymic methodol. is more efficient in the case of the largest alc. (HD) mainly because of the high stability of the immobilized enzymes upon recovery and reuse. In contrast, the use of a base as a catalyst is highly favorable in the case of isopropanol because of the rather poor activity of the lipases and the low price of the bases. With EH, the activity of lipases is good but the recoverability is not as efficient; hence, basic catalysts are again the most attractive alternative. The mixtures of esters obtained may be useful as hydraulic liquids given their viscosity values.

ACS Omega published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kavitha, B.; Sravanthi, M.; Saritha Reddy, P. published the artcile< DNA interaction, docking, molecular modelling and biological studies of o-Vanillin derived Schiff base metal complexes>, Related Products of 5344-90-1, the main research area is copper cobalt chromium zinc vanillin Schiff base complex preparation; transition metal Schiff base DNA binding ESR cytotoxic antimicrobial.

In the present studies, [Cu(ABOVL)] 1, [Co(ABOVL)] 2, [Cr(ABOVL)] 3, and [Zn(ABOVL)] 4 complexes were prepared where ABOVL is the condensation product of 2-hydroxy-3-methoxybenzaldehyde (o-Vanillin) and (2-aminophenyl)methanol (2-aminobenzylalc.). To characterize ABOVL and its metal complexes standard anal. and spectral techniques were employed. From the spectral data, ABOVL acts as a bi-dentate ligand with O, N as donor atoms and complex 1 exhibited square planar geometry and complexes 2, 3, and 4 exhibited octahedral geometries resp. DNA binding studies were performed using fluorescence, viscosity and absorption studies. The binding constant from absorption studies was 6.23 ± 0.04 × 104 M-1, 5.76 ± 0.03 × 104 M-1, 4.95 ± 0.07 × 104 M-1 and 4.12 ± 0.06 × 104 M-1 for 1, 2, 3 and 4 complexes resp., and Stern-Volmer quenching constant, KSV from fluorescence studies was 3.99 × 103 M-1, 3.21 × 103 M-1, 2.78 × 103 M-1 and 2.53 × 103 M-1 for 1, 2, 3 and 4 complexes resp. The above data signifies intercalative mode of binding of complexes to CT-DNA. Viscosity studies further revealed the binding of complexes to CT-DNA through intercalation. Nuclease studies of the complexes were carried out using supercoiled pUC19 DNA with hydrogen peroxide as an oxidant and the results were discussed. GOLO 3.1 program (software) was used for docking studies and the results showed that complexes can effective bind with active receptor protein of DNA topoisomerase I involving hydrogen bonding interactions and the results were discussed. Antimicrobial studies performed by disk diffusion method showed that the complexes possess higher anti-microbial activity than compared to ABOVL. In-vitro cytotoxic studies were performed for the synthesized complexes against selected cell lines by MTT assay where Complex 1 showed potential inhibitory efficiency with an IC50 of 49.13 μg/mL as compared to other complexes. Mol. modeling studies were carried out using Argus laboratory

Journal of Molecular Structure published new progress about Antibacterial agents. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Related Products of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pandey, Akanksha M.; Digrawal, Naveen Kumar; Mohanta, Nirmala; Jamdade, Akash Bandu; Chaudhari, Moreshwar B.; Bisht, Girish Singh; Gnanaprakasam, Boopathy published the artcile< Catalytic Acceptorless Dehydrogenation of Amino Alcohols and 2-Hydroxybenzyl Alcohols for Annulation Reaction under Neutral Conditions>, Quality Control of 5344-90-1, the main research area is dicarbonyl amino alc domino enamine ruthenium oxidative cyclization green; tetrahydroindole preparation; tetrahydroacridinone preparation; hydroxybenzyl alc dicarbonyl ruthenium alkylation cyclization dehydrogenation condensation hydrogenation; tetrahydroxanthenone preparation.

A base-free and acceptorless Ru-catalyzed dehydrogenative approach has been developed for the synthesis of N-heterocycles by using 1,3-dicarbonyls and amino alcs. through a domino sequential enamine formation and intramol. oxidative cyclization strategy. This unified approach is also applicable for the synthesis of O-heterocycles involving 2-hydroxybenzyl alc. as a coupling reactant via consecutive C-alkylation and intramol. cyclization steps. The present protocol is general for the synthesis of varieties of biol. important scaffolds, such as tetrahydro-4H-indol-4-one, 3,4-dihydroacridin-1(2H)-one, and tetrahydro-1H-xanthen-1-ones derivatives using a single catalytic system, viz. RuH2CO(PPh3)3. Environmentally benign H2O and H2 are the only byproducts in this domino process. Moreover, RuH2CO(PPh3)3-catalyzed C3-alkylation of tetrahydro-4H-indol-4-one using alc. as a alkylating partner is also described in this report. For the first time, a solvent-free gram-scale reaction for the acceptorless dehydrogenative annulation has been demonstrated. A plausible mechanism for the Ru-catalyzed base-free and acceptorless dehydrogenative annulation of amino alcs. or 2-hydroxybenzyl alcs. has been provided with several exptl. investigations and spectroscopic evidence.

Journal of Organic Chemistry published new progress about Acridines Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation) (tetrahydroacridinone). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Quality Control of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shui, Hongling; Zhong, Yuhong; Ouyang, Lu; Luo, Nianhua; Luo, Renshi published the artcile< Iridium-Catalyzed Acceptorless Dehydrogenative Coupling of 2-Aminoarylmethanols with Amides or Nitriles to Synthesize Quinazolines>, Application In Synthesis of 5344-90-1, the main research area is quinazoline preparation; aminoarylmethanol amide nitrile acceptorless dehydrogenative coupling iridium catalyst.

An efficient iridium-catalyzed acceptorless dehydrogenative coupling (ADC) reaction for the preparation of various quinazolines from 2-aminoarylmethanols and amides or nitriles had been developed. A wide range of substituted 2-aminobenzyl alcs. and (hetero)aryl or alkyl benzamides and nitriles were well compatible to afford various quinazolines in excellent yields. Merits of this new strategy are the high atom-economy, mild reaction conditions, and simple operation, and the methodol. is suitable for a variety of substrates.

Synthesis published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts