Rajnak, Cyril’s team published research in Dalton Transactions in 2020 | CAS: 1195-59-1

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Name: 2,6-Pyridinedimethanol

《Effect of the distant substituent on the slow magnetic relaxation of the mononuclear Co(II) complex with pincer-type ligands》 was published in Dalton Transactions in 2020. These research results belong to Rajnak, Cyril; Titis, Jan; Moncol’, Jan; Boca, Roman. Name: 2,6-Pyridinedimethanol The article mentions the following:

A hexacoordinated complex [Co(pydm)2](mdnbz)2 from the family of pincer complexes was prepared and structurally characterized. The complex behaves as an S = 3/2 spin system with a considerable zero-field splitting parameter D/hc ~+50 cm-1. The a.c. susceptibility measurements show a slow magnetic relaxation with three relaxation channels: at the low-frequency (LF), intermediate-frequency (IF) and high-frequency (HF) domains. At T = 2.0 K and an external field BDC = 0.25 T, the relaxation times of the individual modes are τ(LF) = 282 ms, τ(IF) = 3.1 ms, and τ(HF) = 0.16 ms, and the mole fractions of the slowly relaxing species are x(LF) = 0.19, x(IF) = 0.45, and x(HF) = 0.37. A comparison with the analogous complex [Co(pydm)2](dnbz)2 possessing a demethylated counteranion and identical metal cation shows that even small modifications in the composition of SIMs are no longer underestimated for the slow magnetic relaxation. In addition to this study using 2,6-Pyridinedimethanol, there are many other studies that have used 2,6-Pyridinedimethanol(cas: 1195-59-1Name: 2,6-Pyridinedimethanol) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Name: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Yu-Zhen’s team published research in Nature Communications in 2019 | CAS: 873-75-6

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Formula: C7H7BrO It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

The author of 《Location determination of metal nanoparticles relative to a metal-organic framework》 were Chen, Yu-Zhen; Gu, Bingchuan; Uchida, Takeyuki; Liu, Jiandang; Liu, Xianchun; Ye, Bang-Jiao; Xu, Qiang; Jiang, Hai-Long. And the article was published in Nature Communications in 2019. Formula: C7H7BrO The author mentioned the following in the article:

Metal nanoparticles (NPs) stabilized by metal-organic frameworks (MOFs) have been intensively studied in recent decades, while investigations on the location of guest metal NPs relative to host MOF particles remain challenging and very rare. In this work, we have developed several characterization techniques, including high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) tomog., hyperpolarized 129Xe NMR spectroscopy and positron annihilation spectroscopy (PAS), which are able to determine the specific location of metal NPs relative to the MOF particle. The fine PdCu NPs confined inside MIL-101 exhibit excellent catalytic activity, absolute selectivity and satisfied recyclability in the aerobic oxidation of benzyl alc. in pure water. As far as we know, the determination for the location of metal NPs relative to MOF particles and pore structure information of metal NPs/MOF composites by 129Xe NMR and PAS techniques has not yet been reported. In the experiment, the researchers used many compounds, for example, (4-Bromophenyl)methanol(cas: 873-75-6Formula: C7H7BrO)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Formula: C7H7BrO It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Markwart, Jens C.’s team published research in Polymer Chemistry in 2019 | CAS: 821-41-0

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Name: 5-Hexen-1-ol

The author of 《First phosphorus AB2 monomer for flame-retardant hyperbranched polyphosphoesters: AB2 vs. A2 + B3》 were Markwart, Jens C.; Battig, Alexander; Kuckhoff, Thomas; Schartel, Bernhard; Wurm, Frederik R.. And the article was published in Polymer Chemistry in 2019. Name: 5-Hexen-1-ol The author mentioned the following in the article:

Branched polymers are an important class of polymers with a high number of terminal groups, lower viscosity compared to their linear analogs and higher miscibility, which makes them especially interesting for flame retardant applications, where the flame retardants (FR) are blended with another polymer matrix. Hyperbranched polyphosphoesters (hbPPEs) are gaining more and more interest in the field of flame retardancy, as low molar mass FRs often have the disadvantage of blooming out or leaching, which is not desired in consumer products. Here, the authors present the first phosphorus-based AB2 monomer for the synthesis of hbPPEs and assess its flame-retardant performance in an epoxy resin compared to a hbPPE synthesized by an A2 + B3 approach. The hbPPE synthesized from an AB2 monomer exhibited a slightly higher performance compared to a similar hbPPE, which was prepared by A2 + B3 polyaddition, probably due to its higher phosphorus content. After reading the article, we found that the author used 5-Hexen-1-ol(cas: 821-41-0Name: 5-Hexen-1-ol)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Name: 5-Hexen-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Biswas, Nandita’s team published research in Dalton Transactions in 2019 | CAS: 873-75-6

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Reference of (4-Bromophenyl)methanol It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

In 2019,Dalton Transactions included an article by Biswas, Nandita; Das, Kalicharan; Sardar, Bitan; Srimani, Dipankar. Reference of (4-Bromophenyl)methanol. The article was titled 《Acceptorless dehydrogenative construction of C=N and C=C bonds through catalytic aza-Wittig and Wittig reactions in the presence of an air-stable ruthenium pincer complex》. The information in the text is summarized as follows:

The construction of C=N bonds was achieved by the dehydrogenative coupling of alcs. ROH (R = CH2C6H5, CH(CH3)C6H5, thiophen-2-ylmethyl, etc.) and azides R1N3 (R1 = C6H5, CH2C6H5, 4-BrC6H4, etc.) via aza-Wittig type reaction. The reaction is catalyzed by an acridine-derived ruthenium pincer complex and does not use any oxidant. The present protocol offers a wide substrate scope, including aliphatic, aryl or heteroaryl alc./azides. This expeditious protocol was successfully applied to construct a C=C bond directly from alc. via dehydrogenative Wittig reaction. Furthermore, the synthesis of structurally important pyrrolo[1,4]benzodiazepine derivatives I and II was also achieved by this methodol. In addition to this study using (4-Bromophenyl)methanol, there are many other studies that have used (4-Bromophenyl)methanol(cas: 873-75-6Reference of (4-Bromophenyl)methanol) was used in this study.

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Reference of (4-Bromophenyl)methanol It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Karimi, Fatemeh’s team published research in Molecular Catalysis in 2019 | CAS: 100-83-4

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Application In Synthesis of 3-Hydroxybenzaldehyde

In 2019,Molecular Catalysis included an article by Karimi, Fatemeh; Zolfigol, Mohammad Ali; Yarie, Meysam. Application In Synthesis of 3-Hydroxybenzaldehyde. The article was titled 《A novel and reusable ionically tagged nanomagnetic catalyst: Application for the preparation of 2-amino-6-(2-oxo-2H-chromen-3-yl)-4-arylnicotinonitriles via vinylogous anomeric based oxidation》. The information in the text is summarized as follows:

Herein, Fe3O4@O2PO2(CH2)2NH3+CF3CO-2 as a novel and reusable ionically tagged nanomagnetic catalyst is reported. It was characterized by several techniques including Fourier transform IR (FT-IR) spectroscopy, thermo gravimetric anal./DTA (TGA/DTA), SEM (SEM), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM) and energy dispersive X-ray (EDX) anal. The catalytic behavior of the Fe3O4@O2PO2(CH2)2NH3+CF3CO-2 was examined for the synthesis of 2-amino-6-(2-oxo-2H-chromen-3-yl)-4-arylnicotinonitrile derivatives Exptl. data approved that the final step of the plausible mechanism proceeded via a vinylogous anomeric based oxidation mechanism. Described catalyst showed excellent potential of recycling and reusing for the described multicomponent reaction. The results came from multiple reactions, including the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Application In Synthesis of 3-Hydroxybenzaldehyde)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Application In Synthesis of 3-Hydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shimoda, Tomoe’s team published research in Inorganic Chemistry in 2018 | CAS: 1195-59-1

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Recommanded Product: 2,6-Pyridinedimethanol

In 2018,Inorganic Chemistry included an article by Shimoda, Tomoe; Morishima, Takeshi; Kodama, Koichi; Hirose, Takuji; Polyansky, Dmitry E.; Manbeck, Gerald F.; Muckerman, James T.; Fujita, Etsuko. Recommanded Product: 2,6-Pyridinedimethanol. The article was titled 《Photocatalytic CO2 Reduction by Trigonal-Bipyramidal Cobalt(II) Polypyridyl Complexes: The Nature of Cobalt(I) and Cobalt(0) Complexes upon Their Reactions with CO2, CO, or Proton》. The information in the text is summarized as follows:

The cobalt complexes CoIIL1(PF6)2 (1; L1 = 2,6-bis[2-(2,2′-bipyridin-6′-yl)ethyl]pyridine) and CoIIL2(PF6)2 (2; L2 = 2,6-bis[2-(4-methoxy-2,2′-bipyridin-6′-yl)ethyl]pyridine) were synthesized and used for photocatalytic CO2 reduction in acetonitrile. X-ray structures of complexes 1 and 2 reveal distorted trigonal-bipyramidal geometries with all nitrogen atoms of the ligand coordinated to the Co(II) center, in contrast to the common six-coordinate cobalt complexes with pentadentate polypyridine ligands, where a monodentate solvent completes the coordination sphere. Under electrochem. conditions, the catalytic current for CO2 reduction was observed near the Co(I/0) redox couple for both complexes 1 and 2 at E1/2 = -1.77 and -1.85 V vs. Ag/AgNO3 (or -1.86 and -1.94 V vs Fc+/0), resp. Under photochem. conditions with 2 as the catalyst, [Ru(bpy)3]2+ as a photosensitizer, tri-p-tolylamine (TTA) as a reversible quencher, and triethylamine (TEA) as a sacrificial electron donor, CO and H2 were produced under visible-light irradiation, despite the endergonic reduction of Co(I) to Co(0) by the photogenerated [Ru(bpy)3]+. However, bulk electrolysis in a wet CH3CN solution resulted in the generation of formate as the major product, indicating the facile production of Co(0) and [Co-H]n+ (n = 1 and 0) under electrochem. conditions. The one-electron-reduced complex 2 reacts with CO to produce [Co0L2(CO)] with νCO = 1894 cm-1 together with [CoIIL2]2+ through a disproportionation reaction in acetonitrile, based on the spectroscopic and electrochem. data. Electrochem. and time-resolved UV-vis spectroscopy indicate a slow CO binding rate with the [CoIL2]+ species, consistent with d. functional theory calculations with CoL1 complexes, which predict a large structural change from trigonal-bipyramidal to distorted tetragonal geometry. The reduction of CO2 is much slower than the photochem. formation of [Ru(bpy)3]+ because of the large structural changes, spin flipping in the cobalt catalytic intermediates, and an uphill reaction for the reduction to Co(0) by the photoproduced [Ru(bpy)3]+. In the experimental materials used by the author, we found 2,6-Pyridinedimethanol(cas: 1195-59-1Recommanded Product: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Recommanded Product: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Brethome, Flavien M.’s team published research in Nature Energy in 2018 | CAS: 1195-59-1

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Recommanded Product: 2,6-Pyridinedimethanol

In 2018,Brethome, Flavien M.; Williams, Neil J.; Seipp, Charles A.; Kidder, Michelle K.; Custelcean, Radu published 《Direct air capture of CO2 via aqueous-phase absorption and crystalline-phase release using concentrated solar power》.Nature Energy published the findings.Recommanded Product: 2,6-Pyridinedimethanol The information in the text is summarized as follows:

Using neg. emissions technologies for the net removal of greenhouse gases from the atm. could provide a pathway to limit global temperature rises. Direct air capture of carbon dioxide offers the prospect of permanently lowering the atm. CO2 concentration, providing that economical and energy-efficient technologies can be developed and deployed on a large scale. Here, we report an approach to direct air capture, at the laboratory scale, using mostly off-the-shelf materials and equipment. First, CO2 absorption is achieved with readily available and environmentally friendly aqueous amino acid solutions (glycine and sarcosine) using a household humidifier. The CO2-loaded solutions are then reacted with a simple guanidine compound, which crystallizes as a very insoluble carbonate salt and regenerates the amino acid sorbent. Finally, effective CO2 release and near-quant. regeneration of the guanidine compound are achieved by relatively mild heating of the carbonate crystals using concentrated solar power. In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Recommanded Product: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Recommanded Product: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Heinzlmeir, Stephanie’s team published research in ChemMedChem in 2017 | CAS: 27489-62-9

trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Application In Synthesis of trans-4-Aminocyclohexanol

In 2017,Heinzlmeir, Stephanie; Lohse, Jonas; Treiber, Tobias; Kudlinzki, Denis; Linhard, Verena; Gande, Santosh Lakshmi; Sreeramulu, Sridhar; Saxena, Krishna; Liu, Xiaofeng; Wilhelm, Mathias; Schwalbe, Harald; Kuster, Bernhard; Medard, Guillaume published 《Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors》.ChemMedChem published the findings.Application In Synthesis of trans-4-Aminocyclohexanol The information in the text is summarized as follows:

The receptor tyrosine kinase EPHA2 has gained attention as a therapeutic drug target for cancer and infectious diseases. However, EPHA2 research and EPHA2-based therapies have been hampered by the lack of selective small-mol. inhibitors. Herein we report the synthesis and evaluation of dedicated EPHA2 inhibitors based on the clin. BCR-ABL/SRC inhibitor dasatinib as a lead structure. We designed hybrid structures of dasatinib and the previously known EPHA2 binders CHEMBL249097, PD-173955, and a known EPHB4 inhibitor in order to exploit both the ATP pocket entrance as well as the ribose pocket as binding epitopes in the kinase EPHA2. Medicinal chem. and inhibitor design were guided by a chem. proteomics approach, allowing early selectivity profiling of the newly synthesized inhibitor candidates. Concomitant protein crystallog. of 17 inhibitor co-crystals delivered detailed insight into the at. interactions that underlie the structure-affinity relationship. Finally, the anti-proliferative effect of the inhibitor candidates was confirmed in the glioblastoma cell line SF-268. In this work, we thus discovered a novel EPHA2 inhibitor candidate that features an improved selectivity profile while maintaining potency against EPHA2 and anticancer activity in SF-268 cells. After reading the article, we found that the author used trans-4-Aminocyclohexanol(cas: 27489-62-9Application In Synthesis of trans-4-Aminocyclohexanol)

trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Application In Synthesis of trans-4-Aminocyclohexanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hodgson, David M.’s team published research in Organic Letters in 2015 | CAS: 18621-18-6

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.HPLC of Formula: 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

In 2015,Hodgson, David M.; Mortimer, Claire L.; McKenna, Jeffrey M. published 《Amine Protection/α-Activation with the tert-Butoxythiocarbonyl Group: Application to Azetidine Lithiation-Electrophilic Substitution》.Organic Letters published the findings.HPLC of Formula: 18621-18-6 The information in the text is summarized as follows:

Tert-Butoxythiocarbonyl (Botc), the long-neglected thiocarbonyl analog of Boc, facilitates (unlike its alkoxycarbonyl cousin) α-lithiation and electrophile incorporation on N-Botc-azetidine e. g.,. I. N,N,N’,N’-endo,endo-Tetramethyl-2,5-diaminonorbornane proved optimal as a chiral ligand, generating adducts with er up to 92:8. Facile deprotection, under conditions that left the corresponding N-Boc systems intact, was achieved using either TFA or via thermolysis in ethanol.Azetidin-3-ol hydrochloride(cas: 18621-18-6HPLC of Formula: 18621-18-6) was used in this study.

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.HPLC of Formula: 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zubar, Viktoriia’s team published research in Organic Letters in 2020 | CAS: 93524-95-9

3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Recommanded Product: 93524-95-9

Zubar, Viktoriia; Sklyaruk, Jan; Brzozowska, Aleksandra; Rueping, Magnus published an article in Organic Letters. The title of the article was 《Chemoselective Hydrogenation of Alkynes to (Z)-Alkenes Using an Air-Stable Base Metal Catalyst》.Recommanded Product: 93524-95-9 The author mentioned the following in the article:

A highly selective hydrogenation of alkynes using an air-stable and readily available manganese catalyst has been achieved. The reaction proceeds under mild reaction conditions and tolerates various functional groups, resulting in (Z)-alkenes and allylic alcs. in high yields. Mechanistic experiments suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperativity. In the experiment, the researchers used 3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9Recommanded Product: 93524-95-9)

3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Recommanded Product: 93524-95-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts