Author: tianli

Application of 63478-76-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 63478-76-2, name is 6-Heptyn-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

To a stirred solution of 6-heptyn-1-ol 812 (3.33 mL, 26.75 mmol) in CH2CI2 (80 mL) at r.t. was added imidazole (1.76 g, 27.01 mmol) and terf-butyldimethylsilyl chloride (4.07 g, 27.01 mmol). The reaction mixture was allowed to stir at r.t. for 24 h. The mixture was then diluted with Et24 and concentrated in vacuo. The crude product was purified by filtration through silica gel to give alkyne 813 (5.68 g, q uant.) as a colourless liquid . Alkyne 813 was used in subsequent synthetic steps without characterisation.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 63478-76-2, 6-Heptyn-1-ol.

Reference:
Patent; AUCKLAND UNISERVICES LIMITED; BRIMBLE, Margaret Anne; WILLIAMS, Geoffrey Martyn; DUNBAR, Peter Roderick; VERDON, Daniel; (184 pag.)WO2017/145097; (2017); A2;,
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Reference of 221285-25-2, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 221285-25-2, name is (2-Amino-6-fluorophenyl)methanol. A new synthetic method of this compound is introduced below.

N-(3-Fluoro-2-(hydroxymethyl)phenyl)pivalamide; Trimethylacetyl chloride (0.25 mL, 1.99 mmol) was added to a solution of (2-amino-6-fluorophenyl)methanol (268 mg, 1.90 mmol) in CH2Cl2 (10 mL) at 0° C., followed by the addition of DIEA (1.0 mL, 5.7 mmol). The mixture was stirred for 1 hr, followed by normal aqueous work-up to afford the expected crude product, N-(3-fluoro-2-(hydroxymethyl)phenyl)pivalamide, as a colorless oil(415 mg, 97percent yield), which was used directly in the next step; 1H NMR (400 MHz, CDCl3) delta ppm 1.29 (s, 9 H), 2.64 (s, 1 H), 4.78 (d, J=4.78 Hz, 2 H), 6.75-6.84 (m, 1 H), 7.23 (td, J=8.62, 5.92 Hz, 1 H), 7.86 (d, J=8.31 Hz, 1 H), 8.97 (s, 1 H); Mass spec. 226.11 (MH+), Calc. for C12H16FNO2 225.12.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,221285-25-2, (2-Amino-6-fluorophenyl)methanol, and friends who are interested can also refer to it.

Reference:
Patent; Bristol-Myers Squibb Company; US2007/259850; (2007); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of 112-27-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 112-27-6, name is 2,2′-(Ethane-1,2-diylbis(oxy))diethanol. This compound has unique chemical properties. The synthetic route is as follows.

Compound 222 is commercially available. 44.48 ml (0.33 mol) of compound 222 was treated with tosyl chloride (25.39 g, 0.13 mol) in pyridine (500mL) for 16 hours. The reaction was then evaporated to an oil, dissolved in EtOAc and washed with water, sat. NaHCO3, brine, and dried over Na2SO4. The ethyl acetate was concentrated to dryness and purified by column chromatography, eluted with EtOAc/hexanes (1:1) followed by 10% methanol in CH2Cl2 to give compound 223 as a colorless oil. LCMS and NMR were consistent with the structure

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 112-27-6, 2,2′-(Ethane-1,2-diylbis(oxy))diethanol.

Reference:
Patent; ISIS PHARMACEUTICALS, INC.; PRAKASH, Thazha, P.; SETH, Punit, P.; SWAYZE, Eric, E.; GROSSMAN, Tamar, R.; MCCALEB, Michael, L.; WATT, Andrew, T.; FREIER, Susan, M.; WO2015/168635; (2015); A2;,
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In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 20605-01-0, name is Diethyl 2,2-bis(hydroxymethyl)malonate, the common compound, a new synthetic route is introduced below. Formula: C9H16O6

General procedure: A solution of diethyl 2,2-bis(hydroxymethyl) malonate(12 mmol), 1 (10 mmol) and sulfonated carbon(1.0 g) were heated to reflux in a mixture of N,N-dimethylformamide(10 mL) and cyclohexane (6 mL)under stirring for 3 h. After cooling to room temperature,the solution was filtered and the solvent was removed in vacuo, the residue was dissolved in EtOAc (15 mL),washed with saturated brine (10 mL × 2) and water(10 mL×2), dried over anhydrous Na2SO4. The solventwas filtered and concentrated to give 2a-2d as colorless oil.

The synthetic route of 20605-01-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Yuan, Lin; Li, Zhong Yan; Zhang, Min; Yuan, Xian You; Zhu, Xiao Qing; Journal of Nanoscience and Nanotechnology; vol. 17; 3; (2017); p. 2201 – 2205;,
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Application of 110-73-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 110-73-6, name is 2-(Ethylamino)ethanol. This compound has unique chemical properties. The synthetic route is as follows.

Potassium carbonate (10.4 g, 75.4 mmol) and 2-(ethylamino)ethanol (6.72 g, 75.4 mmol) were added to a solution of 2-bromo-1-phenylethanone (5.00 g, 25.1 mmol) in acetonitrile (150 ml), and the mixture was stirred at RT overnight. The solids were then removed by filtration, and the filtrate was concentrated under reduced pressure to afford the crude title compound which was used in the next step without further purification. Yield: 5.00 g (85% purity, 82% yield). LC/MS [Method 3]: Rt = 0.44 min; MS (ESIpos): m/z = 208 [M+H]+. 1H-NMR (400 MHz, DMSO-d6): d [ppm] = 7.55-7.48 (m, 2H), 7.37-7.23 (m, 3H), 4.11-4.03 (m, 1H), 3.67-3.59 (m, 1H), 3.48-3.36 (m, 1H), 2.76-2.67 (m, 2H), 2.36-2.26 (m, 1H), 2.16-2.06 (m, 1H), 2.01 (d, 1H), 0.99 (t, 3H).

According to the analysis of related databases, 110-73-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; MUeLLER, Steffen; SCHOHE-LOOP, Rudolf; ORTEGA, HERNANDEZ, Nuria; SUeSSMEIER, Frank; JIMENEZ NUNEZ, Eloisa; BRUMBY, Thomas; LINDNER, Niels; GERDES, Christoph; POOK, Elisabeth; BUCHMUeLLER, Anja; GAUGAZ, Fabienne, Zdenka; LANG, Dieter; ZIMMERMANN, Stefanie; EHRMANN, Alexander, Helmut, Michael; GERISCH, Michael; LEHMANN, Lutz; TIMMERMANN, Andreas; SCHAeFER, Martina; SCHMIDT, Georg; SCHLEMMER, Karl-Heinz; FOLLMANN, Markus; KERSTEN, Elisabeth; WANG, Vivian; GAO, Xiang; WANG, Yafeng; (801 pag.)WO2019/219517; (2019); A1;,
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Reference of 144-19-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 144-19-4, name is 2,2,4-Trimethyl-1,3-pentanediol. This compound has unique chemical properties. The synthetic route is as follows.

General procedure: EXAMPLE 7-1 Oxidation of 2,2-Dimethyl-5-phenylpentane-1,3-diol A sodium chlorite aqueous solution (81.0 mg, 0.717 mmol in H2O (0.4 ml)), and a sodium hypochlorite aqueous solution (0.0146 M, 0.16 ml) were separately and slowly dropped onto an acetonitrile (1.2 ml)-pH 6.8 phosphate buffer (1 M, 0.8 ml) of 2,2-dimethyl-5-phenylpentane-1,3-diol (49.7 mg, 0.239 mmol) and DMN-AZADO (3.97 mg, 0.024 mmol) at room temperature. The mixture was stirred at 25 C. for 1 h, and a pH 2.3 phosphate buffer was added until the mixture was brought to pH 4 or less. The aqueous layer was then saturated with a common salt, and extracted with dichloromethane. The organic layer was dried over sodium sulfate, and the solvent was evaporated under reduced pressure. The resulting residue was dissolved in a diethyl ether solution, and treated with an excess amount of a diazomethane diethyl ether solution to produce a methyl ester product. After evaporating the solvent under reduced pressure, the product was purified by silica gel column chromatography to give a hydroxy ester compound (51.0 mg, 90%)

According to the analysis of related databases, 144-19-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; TOHOKU UNIVERSITY; Iwabuchi, Yoshiharu; Shibuya, Masatoshi; Doi, Ryusuke; US9114390; (2015); B2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Abd El-Hafiz, Dalia R., once mentioned the application of 6149-41-3, Name is Methyl 3-hydroxypropanoate, molecular formula is C4H8O3, molecular weight is 104.1045, MDL number is MFCD00272293, category is alcohols-buliding-blocks. Now introduce a scientific discovery about this category, Product Details of 6149-41-3.

The main goal of this research is direct synthesis of ethanol from methane bi-reforming reaction (H2O/CO2 methane reforming, SCMR) in a single step catalytic process. Smart nano-structured spinel ferrite catalysts with small ratio of Cu or Mn in composite with Fe cluster were prepared using ultrasonic assistance technique. Characterization data indicate the stability of the prepared ferrite structure during calcination step, so it can use for high temperature reaction. From XPS and Raman spectra, cupper ferrite shows deviation from ideal spinel structure, which increases the migration of bulk oxygen into surface to share in catalytic activity. The catalytic activity test was performed at moderate reaction condition (700 degrees C) using CO2 as soft oxidant to avoid methane combustion reaction and steam to release the alcoholic products. The two catalysts show unusual high catalytic activity and stability due to strong synergetic effect between metal and Fe. Cu-Fe gives high selectivity (similar to 50%) toward liquid product (ethanol), while Mn-Fe is more selective (similar to 70%) toward gas product (syngas). Furthermore, the chemical looping step is used to obtain ultra-stable SCMR reaction. The steam activation steps were performed for re-oxidation of reduced catalyst in addition to removal of carbon deposited. (c) 2020 Elsevier Ltd. All rights reserved.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 6149-41-3, Product Details of 6149-41-3.

Reference:
Alcohol – Wikipedia,
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Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Recommanded Product: 1,12-Dodecanediol5675-51-4, Name is 1,12-Dodecanediol, SMILES is OCCCCCCCCCCCCO, belongs to alcohols-buliding-blocks compound. In a article, author is Jeevahan, Jeya, introduce new discover of the category.

Biodiesel has become a promising alternative biofuel that exhibits problems like high cost of feedstock, poor atomisation due to high viscosity, stability issues, poor flow properties and high NOx emissions as compared to conventional diesel. Alcohols have recently drawn much attention as a low cost biofuel that, exhibit problems like low cetane number and miscibility issues. Addition of fuel additives, for example, diethyl ether (DEE), may be effective to overcome the problems with biodiesel or alcohols. In this work, the influence of DEE on engine performance and emissions were investigated for diesel/biodiesel blends, diesel/butanol blends or diesel/pentanol blends. Fuel blends of biodiesel (B20), butanol (BU20), pentanol (PN20), biodiesel with DEE (B20D10), butanol with DEE (BU20D10) and pentanol with DEE (PN20D10) were prepared. Experiments were conducted on a single cylinder diesel engine for varying load conditions at constant speed. Engine performance and emission characteristics were determined and compared.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 5675-51-4. Recommanded Product: 1,12-Dodecanediol.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 3068-00-6, Name is 1,2,4-Butanetriol, SMILES is OCC(O)CCO, in an article , author is Hosseini, Seyed Fakhreddin, once mentioned of 3068-00-6, Name: 1,2,4-Butanetriol.

Biofunctional quadripartite films were developed by adding trans-Cinnamaldehyde (CIN) (0.4, 0.8, and 1.6% w/v) into chitosan (CH)/poly(vinyl alcohol) (PVA)/fish gelatin (FG) matrices. Rheological data revealed that all solutions exhibited shear-thinning and typical entangle polymers solutions behavior. Mechanical results showed that the incorporation of CIN caused a significant increase (p < 0.05) in tensile strength, while a significant decrease was observed in elongation-at-break. With increasing CIN content, the WVP of the films, which were in the range of 0.785-0.995 g mm/kPa h m(2), increased to some extent, whereas the water solubility and water absorption were reduced up to 47 and 87%, respectively. Moreover, water contact angle analysis showed that the inclusion of CIN made the quadripartite film more hydrophobic, in which the highest value achieved was 86.6 +/- 0.75 degrees at theta(t=10). ATR/FT-IR spectroscopy demonstrated the formation of Schiff-base and intermolecular hydrogen bonds between components' functional groups, which enhanced the quadripartite films' thermal stability and mechanical properties. X-ray diffraction analysis suggested compatibility among the components, and changes of the surface of the films were confirmed by SEM and AFM analyses. Likewise, the antimicrobial activity of the CIN-loaded films were proved against Staphylococcus aureus, Listeria monocytogenes, Salmonella enteritidis, and Escherichia coli. The quadripartite films exhibited in vitro DPPH radical scavenging activity (similar to 35.8%) and ferric reducing power at the maximum CIN testing concentration. The findings of this study proved that CIN-doped films could be used as promising inner functional packaging for food products. Interested yet? Read on for other articles about 3068-00-6, you can contact me at any time and look forward to more communication. Name: 1,2,4-Butanetriol.

Reference:
Alcohol – Wikipedia,
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Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Quality Control of Methyl 3-hydroxypropanoate, 6149-41-3, Name is Methyl 3-hydroxypropanoate, molecular formula is C4H8O3, belongs to alcohols-buliding-blocks compound. In a document, author is Wang, Yan-Qin, introduce the new discover.

Recently, artificial intelligence has driven the development of shape memory hydrogels (SMHs) with complicated environmental sensitive abilities. However, current SMHs possess fundamental limitations in terms of their responsive performance and mechanical properties, which severely limits their practical applications. Herein, a triple-network composite hydrogel with Fe3+, NIR light, and thermal responsive abilities is fabricated and developed as multi-SMHs, named as PDA/CMC-Fe3+/PVA hydrogel. In this hydrogel system, the interpenetrating triple network are formed by chemically-physically co-crosslinked polyvinyl alcohol (PVA) networks, and physically crosslinked carboxymethyl cellulose (CMC)-Fe3+ network. In addition, polydopamine (PDA), which is introduced into the hydrogel system by in-situ polymerization way, could not only serve as an energy converter to endow the hydrogel with NIR-based responsive ability, but also enhance its mechanical strength. Remarkably, the as-prepared PDA/CMC-Fe3+/PVA hydrogels with the optimized compositions exhibit relatively excellent mechanical properties (tensile strength = 163.48 +/- 10.42 kPa, elastic modulus = 45.42 +/- 3.96 kPa, toughness = 165.02 +/- 7.01 kJ/m(3)) due to the synergistic effect of the triple-network and PDA doping. Moreover, the composition of the hydrogel is optimized to realize a stable temporary shape and rapid recovery to the permanent shape, which is controlled by Fe3+, NIR irradiation, and thermal stimulus. The resultant hydrogels exhibit not only multi-stimulus responsive abilities, but also programmable multi-shape memory properties. The versatile shape memory properties endow potential for the materials to be used in the field of artificial intelligence.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 6149-41-3. Quality Control of Methyl 3-hydroxypropanoate.

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Alcohol – Wikipedia,
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