Tag: M.W=100-150

Das, Kanu; Yasmin, Eileen; Das, Babulal; Srivastava, Hemant Kumar; Kumar, Akshai published the artcile< Phosphine-free pincer-ruthenium catalyzed biofuel production: high rates, yields and turnovers of solventless alcohol alkylation>, COA of Formula: C8H9FO, the main research area is phosphine pincer ruthenium biofuel solventless alc alkylation.

Phosphine-free pincer-ruthenium carbonyl complexes based on bis(imino)pyridine and 2,6-bis(benzimidazole-2-yl) pyridine ligands have been synthesized. For the β-alkylation of 1-Ph ethanol with benzyl alc. at 140 °C under solvent-free conditions, (Cy2NNN)RuCl2(CO) (0.00025 mol%) in combination with NaOH (2.5 mol%) was highly efficient (ca. 93% yield, 372 000 TON at 12 000 TO h-1). These are the highest reported values hitherto for a ruthenium based catalyst. The β-alkylation of various alc. combinations was accomplished with ease which culminated to give 380 000 TON at 19 000 TO h-1 for the β-alkylation of 1-Ph ethanol with 3-methoxy benzyl alc. DFT studies were complementary to mechanistic studies and indicate the β-hydride elimination step involving the extrusion of acetophenone to be the overall RDS. While the hydrogenation step is favored for the formation of α-alkylated ketone, the alcoholysis step is preferred for the formation of β-alkylated alc. The studies were extended for the upgradation of ethanol to biofuels. Kinetic studies indicate first order dependence on concentration of both the catalyst and ethanol. Phosphine-free catalytic systems operating with unprecedented activity at a very low base loading to couple lower alcs. to higher alcs. of fuel and pharmaceutical importance are the salient features of this report.

Catalysis Science & Technology published new progress about Alkylation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, COA of Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gawali, Suhas Shahaji; Pandia, Biplab Keshari; Pal, Souvik; Gunanathan, Chidambaram published the artcile< Manganese(I)-Catalyzed Cross-Coupling of Ketones and Secondary Alcohols with Primary Alcohols>, Product Details of C8H9FO, the main research area is cross coupling manganese catalyzed ketone primary alc.

Catalytic cross-coupling of ketones and secondary alcs. with primary alcs. is reported. An abundant manganese based pincer catalyst catalyzes the reactions. Low loading of catalyst (2 mol %) and catalytic use of a mild base (5-10 mol %) are sufficient for efficient cross-coupling. Various aryl and heteroaryl ketones are catalytically cross-coupled with primary alcs. to provide the selective α-alkylated products. Challenging α-ethylation of ketones is also attained using ethanol as an alkylating reagent. Further, direct use of secondary alcs. in the reaction results in in situ oxidation to provide the ketone intermediates, which undergo selective α-alkylation. The reaction proceeds via the borrowing hydrogen pathway. The catalyst oxidizes the primary alcs. to aldehydes, which undergo subsequent aldol condensation with ketones, promoted by catalytic amount of Cs2CO3, to provide the α,β-unsaturated ketone intermediates. The hydrogen liberated from oxidation of alcs. is used for hydrogenation of α,β-unsaturated ketone intermediates. Notably either water or water and dihydrogen are the only byproducts in these environmentally benign catalytic processes. Mechanistic studies allowed inferring all the intermediates involved. Dearomatization-aromatization metal-ligand cooperation in the catalyst facilitates the facile O-H bond activation of both primary and secondary alcs. and the resultant manganese alkoxide complexes produce corresponding carbonyl compounds, perhaps via β-hydride elimination. The manganese(I) hydride intermediate plays dual role as it hydrogenates α,β-unsaturated ketones and liberates mol. hydrogen to regenerate the catalytically active dearomatized intermediate. Metal-ligand cooperation allows all the manganese intermediate to exist in same oxidation state (+1) and plays an important role in these catalytic cross-coupling reactions.

ACS Omega published new progress about Cross-coupling reaction. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Product Details of C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schliebe, Christian; Noll, Julian; Scharf, Sebastian; Gemming, Thomas; Seifert, Andreas; Spange, Stefan; Lehmann, Daniel; Zahn, Dietrich R. T.; Fiedler, Benjamin; Friedrich, Joachim; Blaudeck, Thomas; Lang, Heinrich published the artcile< Nitrogen-containing porous carbon materials by twin polymerization>, HPLC of Formula: 52160-51-7, the main research area is nitrogen doping porous carbon hybrid material twin polymerization copolymerization.

The preparation of Si(OCH2cC4H3NR)4 (5, R = Me; 6, R = H) by the reaction of 2-HOCH2-cC4H3NR (3, R = Me; 4, R = H) with SiCl4 in the ratio of 4:1 in the presence of NEt3 is described. The thermal behavior of twin monomers 5 and 6 was investigated by thermogravimetry and differential scanning calorimetry. Compound 6 shows with 93 °C the lowest polymerization temperature for twin monomers reported so far. In addition to the thermal-induced twin polymerization of 5 and 6, the acidic initiation and copolymerization with 2,2′-spiro-bi[4H-1,3,2-benzodioxasiline] was investigated. The resulting hybrid materials were characterized by 1H, 13C{1H}, and 29Si{1H} solid-state NMR spectroscopy confirming the transformation of the SiOCH2 moieties into CH2 groups enabling the formation of the resp. polymers. These results are supported by HAADF-STEM studies, showing the typical microstructuring of a twin polymer. Furthermore, nitrogen-containing porous carbon materials with a surface area between 200 and 800 m2 g-1 and a nitrogen content of up to 9.1% were obtained. The chem. nature of the incorporated nitrogen was investigated by XPS spectroscopy, revealing that mostly pyrrolic nitrogen is observed, but also pyridinic species are present. [Figure not available: see fulltext.].

Colloid and Polymer Science published new progress about Copolymerization. 52160-51-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H9NO, HPLC of Formula: 52160-51-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hedbom, Christina; Helgstrand, Erik; Misiorny, Alfons; Stjernstrom, Nils E.; Westin, Gertrud published the artcile< Potential hypolipidemic agents. II. Preparation of 5-halo-3-pyridylmethanols>, HPLC of Formula: 22620-34-4, the main research area is fluoronicotinate; nicotinate halo reduction; halopyridinemathanol; pyridine methanol halo.

The 3-pyridinemethanols (I, R = Br, Cl, F) were prepared in 40, 52, and 73% yields resp. by NaBH4 or KBH4 reduction of the corresponding Et halonicotinates. 5-Fluoronicotinic acid was prepared in 48% yield by diazotizing 5-aminonicotinic acid in HBF4-THF-H2O and decomposing the resulting salt in refluxing ligroine.

Acta Pharmaceutica Suecica published new progress about 22620-34-4. 22620-34-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H6ClNO, HPLC of Formula: 22620-34-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bettoni, Leo; Gaillard, Sylvain; Renaud, Jean-Luc published the artcile< Iron-Catalyzed α-Alkylation of Ketones with Secondary Alcohols: Access to β-Disubstituted Carbonyl Compounds>, Electric Literature of 403-41-8, the main research area is iron catalyzed alkylation ketone secondary alc borrowing hydrogen.

An iron-catalyzed borrowing hydrogen strategy has been applied in the synthesis of β-branched carbonyl compounds Various secondary benzylic and aliphatic alcs. have been used as alkylating reagents under mild reaction conditions. The ketones have been isolated in good to excellent yield. Deuterium labeling experiments provide evidence that the alc. is the hydride source in this reaction and that no reversible step or hydrogen/deuterium scrambling takes place during the process.

Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Razavi, Seyed Mohammad; Haghtalab, Ali; Khanchi, Ali Reza published the artcile< Optimization of vanadium(V) extraction by 2-ethyl-1-hexanol and the study of extraction reaction mechanism>, Electric Literature of 104-76-7, the main research area is vanadium extraction reaction mechanism thermodn property.

The aims of the present work are to investigate the mechanism and thermodn. of pentavalent vanadium (V(V)) extraction by 2-ethyl-1-hexanol and to optimize the extraction process. The stoichiometry of V(V) extraction reaction and the extraction equilibrium constants at different temperatures were determined using the slope anal. method applied to the exptl. data. It was shown that the extracted V(V) was in the form of HVO3(ROH) in the organic phase. The standard enthalpy and the standard entropy of extraction reaction were calculated as 39.56 kJ/mol and 54.38 J/(mol.K), resp. A statistical exptl. design method, including Plackett-Burman design (PBD) followed by a central composite design (CCD), was employed to obtain the regression models for the prediction of extraction percentages and to optimize the recovery of V(V) from a synthetic leach solution containing Fe(III), U(VI), Si(IV), and Al(III). The accuracy of the predictive models was proven by the anal. of variance (ANOVA). The optimum condition for selective separation of V(V) was: initial pH of 1.9, extractant concentration of 70%volume/volume, and T=59.3°C. Under the optimum condition, the extraction percentages for V(V), Fe(III), U(VI), Si(IV), and Al(III) were 91.3%, 1.7%, 6.3%, 10.6%, 2.7%, resp. Developed models were validated by solvent extraction experiments at optimum conditions.

Minerals Engineering published new progress about Enthalpy. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Electric Literature of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Bai; Mei, Huihui; Chang, Yongxin; Xu, Kuoxi; Yang, Li published the artcile< A novel near-infrared turn-on fluorescent probe for the detection of Fe3+ and Al3+ and its applications in living cells imaging>, Quality Control of 5344-90-1, the main research area is fluorescent probe detection iron aluminum cell imaging; Cells imaging; Fe(3+) and Al(3+); Fluorescent detection.

A new hemicyanidine-based colorimetric-fluorescent probe L (I) has been synthesized and characterized by x-ray single crystal diffraction, NMR, HRMS and other technologies. The probe L serves as a “”turn-on”” probe for the detection of Fe3+ and Al3+ ions in DMF-HEPES system with a high sensitivity and an excellent selectivity. The probe L manifesting the color of the solution containing L turns red on the addition of Fe3+, and turns pink on the addition of Al3+. The fluorescence turn-on detection of Fe3+ and Al3+ ions is attributed to the photo-induced electron transfer (PET) process and the exertion of the chelation-enhanced fluorescence effect (CHEF) mechanism. The results of thin layer silica gel plate coloration experiments also present the same characteristics. Addnl., further the probe L exhibit good cell permeability and could be employed to monitor Fe3+ and Al3+ ions in the living cells.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about Colorimetry. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Quality Control of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hedbom, Christina; Helgstrand, Erik; Misiorny, Alfons; Stjernstrom, Nils E.; Westin, Gertrud published the artcile< Potential hypolipidemic agents. II. Preparation of 5-halo-3-pyridylmethanols>, HPLC of Formula: 22620-34-4, the main research area is fluoronicotinate; nicotinate halo reduction; halopyridinemathanol; pyridine methanol halo.

The 3-pyridinemethanols (I, R = Br, Cl, F) were prepared in 40, 52, and 73% yields resp. by NaBH4 or KBH4 reduction of the corresponding Et halonicotinates. 5-Fluoronicotinic acid was prepared in 48% yield by diazotizing 5-aminonicotinic acid in HBF4-THF-H2O and decomposing the resulting salt in refluxing ligroine.

Acta Pharmaceutica Suecica published new progress about 22620-34-4. 22620-34-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H6ClNO, HPLC of Formula: 22620-34-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bettoni, Leo; Gaillard, Sylvain; Renaud, Jean-Luc published the artcile< Iron-Catalyzed α-Alkylation of Ketones with Secondary Alcohols: Access to β-Disubstituted Carbonyl Compounds>, Electric Literature of 403-41-8, the main research area is iron catalyzed alkylation ketone secondary alc borrowing hydrogen.

An iron-catalyzed borrowing hydrogen strategy has been applied in the synthesis of β-branched carbonyl compounds Various secondary benzylic and aliphatic alcs. have been used as alkylating reagents under mild reaction conditions. The ketones have been isolated in good to excellent yield. Deuterium labeling experiments provide evidence that the alc. is the hydride source in this reaction and that no reversible step or hydrogen/deuterium scrambling takes place during the process.

Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Razavi, Seyed Mohammad; Haghtalab, Ali; Khanchi, Ali Reza published the artcile< Optimization of vanadium(V) extraction by 2-ethyl-1-hexanol and the study of extraction reaction mechanism>, Electric Literature of 104-76-7, the main research area is vanadium extraction reaction mechanism thermodn property.

The aims of the present work are to investigate the mechanism and thermodn. of pentavalent vanadium (V(V)) extraction by 2-ethyl-1-hexanol and to optimize the extraction process. The stoichiometry of V(V) extraction reaction and the extraction equilibrium constants at different temperatures were determined using the slope anal. method applied to the exptl. data. It was shown that the extracted V(V) was in the form of HVO3(ROH) in the organic phase. The standard enthalpy and the standard entropy of extraction reaction were calculated as 39.56 kJ/mol and 54.38 J/(mol.K), resp. A statistical exptl. design method, including Plackett-Burman design (PBD) followed by a central composite design (CCD), was employed to obtain the regression models for the prediction of extraction percentages and to optimize the recovery of V(V) from a synthetic leach solution containing Fe(III), U(VI), Si(IV), and Al(III). The accuracy of the predictive models was proven by the anal. of variance (ANOVA). The optimum condition for selective separation of V(V) was: initial pH of 1.9, extractant concentration of 70%volume/volume, and T=59.3°C. Under the optimum condition, the extraction percentages for V(V), Fe(III), U(VI), Si(IV), and Al(III) were 91.3%, 1.7%, 6.3%, 10.6%, 2.7%, resp. Developed models were validated by solvent extraction experiments at optimum conditions.

Minerals Engineering published new progress about Enthalpy. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Electric Literature of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts