Tag: 200-300

《Dual Active Site of the Azo and Carbonyl-Modified Covalent Organic Framework for High-Performance Li Storage》 was published in ACS Energy Letters in 2020. These research results belong to Zhao, Genfu; Zhang, Yuhao; Gao, Zhihui; Li, Huani; Liu, Shuming; Cai, Sheng; Yang, Xiaofei; Guo, Hong; Sun, Xueliang. Recommanded Product: 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde The article mentions the following:

Organic electrode materials play a crucial role in environmentally friendly and sustainable lithium-ion batteries (LIBs) due to their abundance, high theor. capacity, inexpensiveness, and recyclability. However, critical issues such as fewer redox-active sites and poor structural stability limit their extensive application in LIBs. Herein, a unique covalent organic framework (Tp-Azo-COF) with a dual active site of N=N and C=O is designed and successfully applied as the anode material for LIBs. Benefiting from its abundance of active sites, large conjugate structure, large surface area, and accessible Li+ transport channels, the Tp-Azo-COF anode materials present high electrochem. kinetics and structural stability. The assembled LIBs deliver a specific capability of 305.97 mAh g-1 at a c.d. of 1000 mA g-1 after 3000 cycles. This work may inspire avenues for the development of advanced organic materials of inexpensive, sustainable, and durable rechargeable batteries. In the experiment, the researchers used 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4Recommanded Product: 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde)

2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4) is a member of phloroglucinol derivatives.Recommanded Product: 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehydeFor acyl phloroglucinols, it is considered the largest category of compounds among phloroglucinols of natural characteristics.

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Safety of 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneOn March 14, 2019, Dong, Jie; Guo, Hui; Peng, Wei; Hu, Qiao-Sheng published an article in Tetrahedron Letters. The article was 《Room temperature Pd(0)/Ad3P-catalyzed coupling reactions of aryl chlorides with bis(pinacolato)diboron》. The article mentions the following:

Room temperature Pd(0)/Ad3P-catalyzed cross-coupling reactions of aryl chlorides with bis(pinacolato)diboron are described. The Pd(0)/Ad3P catalyst, generated from Ad3P-coordinated acetanilide-based palladacycle complex, proved to be an efficient catalyst system for the Miyaura borylation reactions of a variety of aryl chlorides with bis(pinacolato)diboron. The mild reaction condition, the easy availability of the catalyst and good coupling yields make these reactions potentially useful in organic synthesis. In the experiment, the researchers used 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0Safety of 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0) belongs to hydroxy-containing compounds. Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack this functional group.Safety of 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Organic compounds, which are often poorly soluble in water, become water-soluble when they contain two or more hydroxy groups, as illustrated by sugars and amino acid.

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Computed Properties of C12H20O6On March 14, 2022, Schoch, Silvia; Iacopini, Dalila; Dalla Pozza, Maria; Di Pietro, Sebastiano; Degano, Ilaria; Gasser, Gilles; Di Bussolo, Valeria; Marchetti, Fabio published an article in Organometallics. The article was 《Tethering Carbohydrates to the Vinyliminium Ligand of Antiproliferative Organometallic Diiron Complexes》. The article mentions the following:

Four propargyl O-glycosides derivatized with mannose, glucose, and fructose moieties were synthesized and then incorporated within a diiron structure as part of a vinyliminium ligand. Hence, six glycoconjugated diiron complexes, [2-5]CF3SO3 (see Scheme 1) and the nonglycosylated analogs [6a-b]CF3SO3, were obtained in high yields and unambiguously characterized by elemental anal., mass spectrometry, and IR and multinuclear NMR spectroscopies. All compounds exhibited a significant stability in DMSO-d6/D2O solution, with 63-89% of the complexes unaltered after 72 h at 37° and also in the cell culture medium. The cytotoxicity of [2-6]CF3SO3, as well as that of previously reported 7 and 8, was assessed on CT26 (mouse colon carcinoma), U87 (human glioblastoma), MCF-7 (human breast adenocarcinoma), and RPE-1 (human normal retina pigmented epithelium) cell lines. In general, the IC50 values correlate with the hydrophobicity of the compounds (measured as octanol-H2O partition coefficients) and do not show an appreciable level of selectivity against cancer cells with respect to the nontumor ones. In addition to this study using ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, there are many other studies that have used ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6Computed Properties of C12H20O6) was used in this study.

((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6) is a useful reactant for examining the effectiveness of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-​II (CA-​II)​.Computed Properties of C12H20O6 And it is used as chiral auxiliaries in Michael and Aldol addition reactions.

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Name: 5-(tert-Butyl)-4-hydroxyisophthalaldehydeOn September 2, 2013 ,《One-pot regioselective synthesis of imidazole and 2,3-dihydroquinazolinone derivatives – an easy access to “”nature-like molecules””; part XIII in the series: “”studies on novel synthetic methodologies””》 was published in Synlett. The article was written by Sashidhara, Koneni V.; Palnati, Gopala Reddy; Dodda, Ranga Prasad; Avula, Srinivasa Rao; Swami, Priyanka. The article contains the following contents:

A mild and highly practical regioselective synthesis of imidazole and 2,3-dihydroquinazolinone derivatives from 5-alkyl-4-hydroxyisophthalaldehydes with suitable substrates in acetic acid is reported. Further exploration of the mol. diversity of 2,3-dihydroquinazolinone is demonstrated by the synthesis of diverse pharmacol. relevant natural-product-like scaffolds. In the experiment, the researchers used 5-(tert-Butyl)-4-hydroxyisophthalaldehyde(cas: 153759-59-2Name: 5-(tert-Butyl)-4-hydroxyisophthalaldehyde)

5-(tert-Butyl)-4-hydroxyisophthalaldehyde(cas: 153759-59-2) belongs to phenols.Name: 5-(tert-Butyl)-4-hydroxyisophthalaldehydeDeprotonation of a phenol forms a corresponding negative phenolate ion or phenoxide ion, and the corresponding salts are called phenolates or phenoxides (aryloxides according to the IUPAC Gold Book).

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《Direct Synthesis of Deuterium-Labeled O -, S -, N -Vinyl Derivatives from Calcium Carbide》 was written by Ledovskaya, Maria S.; Voronin, Vladimir V.; Rodygin, Konstantin S.; Posvyatenko, Alexandra V.; Egorova, Ksenia S.; Ananikov, Valentine P.. Synthetic Route of C12H20O6 And the article was included in Synthesis on August 31 ,2019. The article conveys some information:

A novel methodol. for the preparation of trideuterovinyl derivatives such as I [R = n-decyl, menthyl, Ph, etc.; X = O, S] and II [R1 = indol-1-yl, NPh2, carbazol-9-yl, etc.] of high purity directly from alcs., thiols, and NH-compounds was developed. Com. available calcium carbide and D2O acted as a D2-acetylene source and DMSO-d6 was used to complete the formation of the D2C=C(D)-X fragment (X = O, S, N). Polymerization of a selected trideuterovinylated compound showed a very promising potential of these substances in the synthesis of labeled polymeric materials. Biol. activity of the synthesized trideuterovinyl derivatives was evaluated and the results indicated a significant increase of cytotoxicity upon deuteration. The experimental process involved the reaction of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6Synthetic Route of C12H20O6)

((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6) is a useful reactant for examining the effectiveness of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-​II (CA-​II)​.Synthetic Route of C12H20O6 And it is used as chiral auxiliaries in Michael and Aldol addition reactions.

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Quality Control of Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrateIn 2017 ,《Root hairs as biotemplates for fabricating hollow double-layer CuO microtubes》 was published in Materials Letters. The article was written by Chen, Gongyun; Yang, Xiaojun; Miao, Kai; Long, Mengying; Deng, Wenli. The article contains the following contents:

Hollow double-layer CuO microtubes are fabricated by electroless deposition using root hairs of Syngonium podophyllum as biotemplates. It is a new efficient biotemplate for fabricating tubular microstructures because of its reproducible and eco-friendly characteristics. The fabricated microtubes showed unique double-layer structures and the thickness of tubular wall can be adjusted by controlling the deposition time. It was indicated that the microtubes comprised of pure monoclinic CuO with good crystallinity based on XRD and TEM anal. Gas sensing investigation suggested the hollow double-layer CuO microtubes exhibited good gas sensing performance toward isopropanol.Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5Quality Control of Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate) was used in this study.

Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5) is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient. Quality Control of Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate Potassium sodium tartrate tetrahydrate has been used in the preparation of Lowry reagent for the determination of microsomal protein concentration in rat hepatic microsomes by Lowry method.

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Product Details of 78782-17-9In 2019 ,《Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal》 appeared in Organic Letters. The author of the article were Apel, Caroline; Kasper, Marc-Andre; Stieger, Christian E.; Hackenberger, Christian P. R.; Christmann, Mathias. The article conveys some information:

A new lysine-reactive cyclopropropyl aldehyde for the covalent modification of proteins was developed. The reagent exploits a divinylcyclopropane-cycloheptadiene rearrangement to render the initial condensation irreversible. A labeling study on eGFP demonstrated excellent chemoselectivity for the modification of amine-nucleophiles with the possibility of subsequent modifications.Bis[(pinacolato)boryl]methane(cas: 78782-17-9Product Details of 78782-17-9) was used in this study.

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.Product Details of 78782-17-9 Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.

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Gayraud, Oscar; Laroche, Benjamin; Casaretto, Nicolas; Nay, Bastien published their research in Organic Letters in 2021. The article was titled 《Synthesis of a Biomimetic Tetracyclic Precursor of Aspochalasins and Formal Synthesis of Trichoderone A》.SDS of cas: 78782-17-9 The article contains the following contents:

Aspochalasins are leucine-derived cytochalasins. Their complexity is associated with a high degree of biosynthetic oxidation, herein inspiring a two-phase strategy in total synthesis. We thus describe the synthesis of a putative biomimetic tetracyclic intermediate. The constructive steps are an intramol. Diels-Alder reaction to install the isoindolone core of cytochalasins, whose branched precursor was obtained from a stereoselective Ireland-Claisen rearrangement performed from a highly unsaturated substrate. This also constitutes a formal synthesis of trichoderone A. In the experiment, the researchers used Bis[(pinacolato)boryl]methane(cas: 78782-17-9SDS of cas: 78782-17-9)

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.SDS of cas: 78782-17-9 Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.

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《Pd/Cu-Catalyzed Domino Cyclization/Deborylation of Alkene-Tethered Carbamoyl Chloride and 1,1-Diborylmethane》 was written by Zhang, Chenhuan; Wu, Xianqing; Wang, Chenchen; Zhang, Chengxi; Qu, Jingping; Chen, Yifeng. Recommanded Product: Bis[(pinacolato)boryl]methane And the article was included in Organic Letters in 2020. The article conveys some information:

Reported herein is a Pd/Cu cooperative-catalyzed dicarbofunctionalization of alkene-tethered carbamoyl chlorides with 1,1-diborylmethane. This cyclization/deborylation cascade strategy allows for the expedient formation of the versatile borylated 3,3-disubstituted oxindole skeleton, allowing for further functionalization via the derivatization of the C-B bond. In the experimental materials used by the author, we found Bis[(pinacolato)boryl]methane(cas: 78782-17-9Recommanded Product: Bis[(pinacolato)boryl]methane)

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.Recommanded Product: Bis[(pinacolato)boryl]methane Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.

Referemce:
Alcohol – Wikipedia,
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《No-wash live cell imaging with a photoswitchable near-infrared hCRBPII protein-fluorophore tag》 was written by Sheng, Wei; Geiger, James H.; Borhan, Babak. Formula: C4H12KNaO10 And the article was included in Methods in Enzymology in 2020. The article conveys some information:

Fluorescence cell imaging provides a powerful tool to study biol. processes including regulation, protein-protein interaction, trafficking, development, cellular structure and morphol., to name a few. Complimentary to fluorescent proteins (FPs), the development of multiple site-selective labeling techniques offer choice and flexibility in selection of fluorophores for optimal exptl. design. Near-IR (NIR) labels are highly desired since they enable deeper imaging depths and cleaner optical windows. Photochromic labels are also desirable since they provide the capability to control the fluorescence “”turn-ON”” and in some cases “”turn-OFF”” functionality. In addition, no-wash labeling techniques can greatly simplify exptl. procedures and offer real-time imaging options. Also, compared to most of the regular FPs, these systems are often matured rapidly and do not need mol. oxygen for activation. Here, we present a no-wash photochromic NIR fluorescence live cell imaging approach. This method uses engineered human Cellular Retinol Binding Protein II (hCRBPII) as a genetically encodable tag and a solvatochromic dye FR-1V as the fluorophore. At the heart of this system, a photo-triggered switching between NIR “”OFF”” and “”ON”” modes provide spatiotemporal control for subcellular fluorescence imaging. The experimental process involved the reaction of Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5Formula: C4H12KNaO10)

Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5) is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient. Formula: C4H12KNaO10 It may be used as a constituent to prepare DNS (3,5- dinitrosalicylic acid) reagent and Fehling′s solution B, which are used in the determination of reducing sugar.

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