Tag: 100-200

《Indan-f-amphox: an efficient PNN ligand for iridium-catalyzed asymmetric hydrogenation of β-aryl β-ketoestersã€?was published in Youji Huaxue in 2020. These research results belong to Gu, Guoxian; Hu, Yang; Liu, Shaodong; Dong, Xiuqin; Zhang, Xumu. SDS of cas: 126456-43-7 The article mentions the following:

A new chiral tridentate PNN ligand, indan-f-amphox (a sister ligand of f-amphox), was synthesized and applied in iridium-catalyzed asym. hydrogenation of β-aryl β-ketoesters. A wide range of β-aryl β-ketoesters are reduced using an Ir (III)-indan-f-amphox catalyst with excellent enantioselectivities and reactivities (up to 99% ee, TON=10000). In addition to this study using (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, there are many other studies that have used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7SDS of cas: 126456-43-7) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.SDS of cas: 126456-43-7

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HPLC of Formula: 873-75-6In 2019 ,《Polymer-Anchored Bifunctional Pincer Catalysts for Chemoselective Transfer Hydrogenation and Related Reactionsã€?appeared in ChemSusChem. The author of the article were Mujahed, Shrouq; Valentini, Federica; Cohen, Shirel; Vaccaro, Luigi; Gelman, Dmitri. The article conveys some information:

A series of polymer-supported cooperative PC(sp3)P pincer catalysts was synthesized and characterized. Their catalytic activity in the acceptorless dehydrogenative coupling of alcs. to form β-alkylated ketones and the transfer hydrogenation of aldehydes to form benzyl alcs. using formic acid as a hydrogen source was investigated. This comparative study, examining homogeneous and polymer-tethered species, proved that carefully designing a link between the support and the catalytic moiety, which takes into consideration the mechanism underlying the target transformation, might lead to superior heterogeneous catalysis. The experimental process involved the reaction of (4-Bromophenyl)methanol(cas: 873-75-6HPLC of Formula: 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.HPLC of Formula: 873-75-6 It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

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Recommanded Product: 4048-33-3In 2019 ,《Polymaleimide-Based Polysulfobetaines Bearing Functional and Nonfunctional Hydrophobic Units and Its Aggregation Behavior in Aqueous Mediaã€?appeared in Langmuir. The author of the article were Dsouza, Roshan F.; Parthiban, Anbanandam. The article conveys some information:

Copolymaleimide-based zwitterionic polysulfobetaines (PM-SBs) were prepared by a “”top down”” method for the first time. Interfacial studies of these polymers showed many interesting characteristics. These PM-SBs did not require any salt in the form of sodium chloride (NaCl) to dissolve in water and exhibited exceptional salt tolerance. PM-SBs showed very mild thermogelling behavior. The viscosity of 5 weight % aqueous solution of polymers increased with increasing concentration of salt without showing any limits within the salt concentrations studied [200g/L of NaCl (3.4 M)] in contrast to other reported zwitterionic polysulfobetaines. Dynamic light scattering (DLS) studies also indicated a structure-dependent particle size with varying concentrations of NaCl solution The uniformity of particles of 5 weight % aqueous solution of PM-SBs increased with increasing concentration of NaCl. At 0.1 weight % concentration, even in the absence of NaCl, mild aggregation was noticed. The concentration of aggregated particles increased with the increasing concentration of NaCl. Because of the exceptionally high salt tolerance, these polymers are potentially suitable for applications in antifouling, oil field, personal care formulations, and water purification The experimental process involved the reaction of 6-Aminohexan-1-ol(cas: 4048-33-3Recommanded Product: 4048-33-3)

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Recommanded Product: 4048-33-3

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In 2022,Ma, Zhuang; Zhou, Bei; Li, Xinmin; Kadam, Ravishankar G.; Gawande, Manoj B.; Petr, Martin; Zboril, Radek; Beller, Matthias; Jagadeesh, Rajenahally V. published an article in Chemical Science. The title of the article was 《Reusable Co-nanoparticles for general and selective N-alkylation of amines and ammonia with alcoholsã€?Quality Control of 3-Pyridinemethanol The author mentioned the following in the article:

A general cobalt-catalyzed N-alkylation of amines with alcs. by borrowing hydrogen methodol. to afford alkylated amines I [R = Pr-n, cyclohexyl, Ph, etc.; R1 = Ph, 4-MeC6H4, 4-FC6H4, etc.] was reported. The optimal catalyst for this transformation was prepared by pyrolysis of a specific templated material, which was generated in situ by mixing cobalt salts, nitrogen ligands and colloidal silica and subsequent removal of silica. Applying this novel Co-nanoparticle-based material, >100 primary, secondary and tertiary amines including N-methylamines and selected drug mols. were conveniently prepared starting from inexpensive and easily accessible alcs. and amines or ammonia. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Quality Control of 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Quality Control of 3-Pyridinemethanol

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In 2022,Wang, Xiao-Xu; Yu, Lu; Lu, Xi; Zhang, Zhi-Lin; Liu, De-Guang; Tian, Changlin; Fu, Yao published an article in CCS Chemistry. The title of the article was 《NiH-catalyzed reductive hydrocarbonation of enol esters and ethersã€?Application of 821-41-0 The author mentioned the following in the article:

Chiral dialkyl carbinols and their derivatives are significant synthetic building blocks in organic chem. and related fields. The development of convenient and efficient methods to access these compounds has long been an important endeavor. Herein, authors report a NiH-catalyzed reductive hydroalkylation and hydroarylation of enol esters and ethers. α-Oxoalkyl organonickel species were generated in situ in a catalytic mode and then participated in cross-coupling with alkyl or aryl halides. This approach enabled C(sp3)-C(sp3) and C(sp3)-C(sp2) bond formation under mild reductive conditions with simple operations, thereby boosting a broad substrate scope and good functional compatibility. Esters of enantioenriched dialkyl carbinols were accessed in a catalytic asym. version. Mechanistic studies demonstrated that this reaction proceeded through a syn-addition of Ni-H intermediate to an enol ester with high regio- and enantioselectivity. After reading the article, we found that the author used 5-Hexen-1-ol(cas: 821-41-0Application of 821-41-0)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Application of 821-41-0

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Yang, Han; Chen, Zhen; Guo, Wenjing; Gu, Zhenhua published an article in 2022. The article was titled 《Synthesis of 2-Aryl Azetidines through Pd-Catalyzed Migration/Coupling of 3-Iodoazetidines and Aryl Boronic Acidsã€? and you may find the article in Organic Letters.Synthetic Route of C3H8ClNO The information in the text is summarized as follows:

A palladium-catalyzed cross-coupling of 3-iodoazetidines and nonheteroaryl boronic acids was reported. The [1,1′-biphenyl]-2-yldicyclohexylphosphane ligand enabled the reaction that favored the formation of 2-aryl azetidines. The control experiments indicated that the reaction can proceed through either a palladium-hydride/dihydroazete complex or free dihydroazete intermediate followed by hydropalladation.Azetidin-3-ol hydrochloride(cas: 18621-18-6Synthetic Route of C3H8ClNO) was used in this study.

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Synthetic Route of C3H8ClNO Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

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Kappauf, Katrin; Majstorovic, Nikola; Agarwal, Seema; Rother, Dorte; Claassen, Christiane published an article in 2021. The article was titled 《Modulation of Transaminase Activity by Encapsulation in Temperature-Sensitive Poly(N-acryloyl glycinamide) Hydrogelsã€? and you may find the article in ChemBioChem.Safety of 3-Hydroxybenzaldehyde The information in the text is summarized as follows:

Smart hydrogels hold much potential for biocatalysis, not only for the immobilization of enzymes, but also for the control of enzyme activity. We investigated upper critical solution temperature-type poly N-acryloyl glycinamide (pNAGA) hydrogels as a smart matrix for the amine transaminase from Bacillus megaterium (BmTA). Phys. entrapment of BmTA in pNAGA hydrogels results in high immobilization efficiency (>89%) and high activity (97%). The temperature-sensitiveness of pNAGA is preserved upon immobilization of BmTA and shows a gradual deswelling upon temperature reduction While enzyme activity is mainly controlled by temperature, deactivation tended to be higher for immobilized BmTA (=62-68%) than for free BmTA (=44%), suggesting a deactivating effect due to deswelling of the pNAGA gel. Although the deactivation in response to hydrogel deswelling is not yet suitable for controlling enzyme activity sufficiently, it is nevertheless a good starting point for further optimization. In the experimental materials used by the author, we found 3-Hydroxybenzaldehyde(cas: 100-83-4Safety of 3-Hydroxybenzaldehyde)

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Safety of 3-Hydroxybenzaldehyde

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Xia, Yu-Yan; Lv, Qing-Yang; Yuan, Hua; Wang, Jia-Yi published an article in 2021. The article was titled 《Selective oxidation of alcohols to nitriles with high-efficient Co-[Bmim]Br/C catalyst systemã€? and you may find the article in Chemical Papers.Computed Properties of C6H7NO The information in the text is summarized as follows:

An efficient method for catalyzing the ammoxidation of aromatic alcs. to aromatic nitriles was developed, in which a new heterogeneous catalyst based on transition metal elements was employed, the new catalyst was named Co-[Bmim]Br/C-700 and then characterized by X-ray photo-electronic spectroscopy, transmission electron microscope and X-ray diffraction. The reaction was carried out by two consecutive dehydrogenations under the catalysis of Co-[Bmim]Br/C-700, which catalytically oxidized the alc. to the aldehyde, and then the aldehyde was subjected to ammoxidation to the nitrile. The catalyst system was suitable for a wide range of substrates and nitriles obtained in high yields, especially, the conversion rate of benzyl alc., 4-methoxybenzyl alc., 4-chlorobenzyl alc. and 4-nitrobenzyl alc. reached 100%. The substitution of ammonia and oxygen for toxic cyanide to participate in the reaction accords with the theory of green chem. The results came from multiple reactions, including the reaction of 3-Pyridinemethanol(cas: 100-55-0Computed Properties of C6H7NO)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Computed Properties of C6H7NO

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Frost, James R.; Cheong, Choon Boon; Akhtar, Wasim M.; Caputo, Dimitri F. J.; Christensen, Kirsten E.; Stevenson, Neil G.; Donohoe, Timothy J. published an article in 2021. The article was titled 《Hydrogen borrowing catalysis using 1° and 2° alcohols: Investigation and scope leading to α and β branched productsã€? and you may find the article in Tetrahedron.Recommanded Product: 100-55-0 The information in the text is summarized as follows:

The alkylation of a variety of ketones, e.g., 1-cyclopropyl-3-(furan-2-yl)propan-1-one using 1° R1OH (R1 = n-Bu, Bn, cyclopropylmethyl, etc.) or 2° alcs. R2R3CHOH (R2 = Me, Et; R3 = Et, Ph, thiophen-2-yl, cyclobutyl, etc.; R2R3 = cyclohexyl, 1,4-dioxaspiro[4.5]decan-8-yl, cyclopentyl, etc.) under hydrogen borrowing catalysis is described. Initial research focused on the α-alkylation of cyclopropyl ketones with higher 1° alcs. (i.e. larger than MeOH), leading to the formation of α-branched products, e.g., 1-cyclopropyl-2-(furan-2-ylmethyl)hexan-1-one. The search for addnl. substrates with which to explore this chem. led to discover that di-ortho-substituted aryl ketones were also privileged scaffolds, with Ph* (C6Me5) ketones being the optimal choice. Further investigations revealed that this motif was crucial for alkylation with 2° alcs. forming β-branched products, which also provided an opportunity to study diastereoselective and intramol. hydrogen borrowing processes. The experimental process involved the reaction of 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cmâˆ?1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 100-55-0

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Wu, Peng-yu; Lu, Guo-ping; Cai, Chun published an article in 2021. The article was titled 《Synthesis of an Fe-Pd bimetallic catalyst for N-alkylation of amines with alcohols via a hydrogen auto-transfer methodologyã€? and you may find the article in Green Chemistry.Product Details of 873-75-6 The information in the text is summarized as follows:

Hydrogen auto-transfer (HAT) or borrowing hydrogen (BH) methodol. which combines dehydrogenation, intermediate reaction and hydrogenation, is recognized as an excellent strategy for one-pot synthesis from an economic and environmental point of view. Although much effort has been made on the development of catalysts for HAT reactions, harsh conditions, external base or large amounts of noble metals are still required in most reported catalysis systems, and thus the exploration of a highly efficient and recyclable heterogeneous catalyst remains meaningful. In this work, a novel bimetallic catalyst, Fe10Pd1/NC500 derived from bimetallic MOF NH2-MIL-101(Fe10Pd1), has been prepared, and the catalyst exhibits superior catalytic performance for the N-alkylation of amines with alcs. via a hydrogen auto-transfer methodol. High yields of the desired products were achieved at 120° with an alc./amine molar ratio of 2 : 1 and required no external additive or solvent. A distinct enhancement in catalytic performance is observed when compared with monometallic catalysts, which can be ascribed to the “”synergistic effects”” inside the bimetallic alloys. The N-doped carbon support has been revealed to provide the necessary basicity which avoids the requirement of an external base. Moreover, a wide substrate range and remarkable reusability have been shown by Fe10Pd1/NC500, and this work highlights new possibilities for bimetallic catalysts applied in sustainable chem.(4-Bromophenyl)methanol(cas: 873-75-6Product Details of 873-75-6) was used in this study.

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Product Details of 873-75-6 It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

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