Tag: 100-200

Li, Weikang; Huang, Ming; Liu, Jiahao; Huang, Yong-Liang; Lan, Xiao-Bing; Ye, Zongren; Zhao, Cunyuan; Liu, Yan; Ke, Zhuofeng published their research in ACS Catalysis in 2021. The article was titled 《Enhanced Hydride Donation Achieved Molybdenum Catalyzed Direct N-Alkylation of Anilines or Nitroarenes with Alcohols: From Computational Design to Experiment》.COA of Formula: C6H7NO The article contains the following contents:

An example of homogeneous Mo-catalyzed direct N-alkylation of anilines or nitroarenes with alcs. is presented. The DFT aimed design suggested the easily accessible bis-NHC-Mo(0) complex features a strong hydride-donating ability, achieving effective N-alkylation of anilines or challenging nitroarenes with alcs. The enhanced hydride-donating strategy should be useful in designing highly active systems for borrowing hydrogen transformations. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0COA of Formula: C6H7NO)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.COA of Formula: C6H7NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qiu, Chuntian; Sun, Yangyang; Xu, Yangsen; Zhang, Bing; Zhang, Xu; Yu, Lei; Su, Chenliang published their research in ChemSusChem in 2021. The article was titled 《Photoredox-Catalyzed Simultaneous Olefin Hydrogenation and Alcohol Oxidation over Crystalline Porous Polymeric Carbon Nitride》.HPLC of Formula: 100-55-0 The article contains the following contents:

Booming of photocatalytic water splitting technol. (PWST) opens a new avenue for the sustainable synthesis of high-value-added hydrogenated and oxidized fine chems., in which the design of efficient semiconductors for the in-situ and synergistic utilization of photogenerated redox centers are key roles. Herein, a porous polymeric carbon nitride (PPCN) with a crystalline backbone was constructed for visible light-induced photocatalytic hydrogen generation by photoexcited electrons, followed by in-situ utilization for olefin hydrogenation. Simultaneously, various alcs. were selectively transformed to valuable aldehydes or ketones by photoexcited holes. The porosity of PPCN provided it with a large surface area and a short transfer path for photogenerated carriers from the bulk to the surface, and the crystalline structure facilitated photogenerated charge transfer and separation, thus enhancing the overall photocatalytic performance. High reactivity and selectivity, good functionality tolerance, and broad reaction scope were achieved by this concerted photocatalysis system. The results contribute to the development of highly efficient semiconductor photocatalysts and synergistic redox reaction systems based on PWST for high-value-added fine chem. production The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0HPLC of Formula: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.HPLC of Formula: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Anti-recurrence/metastasis and chemosensitization therapy with thioredoxin reductase-interfering drug delivery system》 was written by Yang, Jichun; Pan, Shuojiong; Gao, Shiqian; Dai, Yiheng; Xu, Huaping. Electric Literature of C3H7BrO And the article was included in Biomaterials in 2020. The article conveys some information:

Thioredoxin reductase (TrxR) is an essential mammalian enzyme that possesses a selenocysteine active site. TrxR is overexpressed in many malignant tumors and has a close relationship with apoptosis, drug resistance, recurrence and metastasis of tumors. Recently, TrxR has emerged as a promising target for anticancer therapy. Herein, we developed a TrxR-interfering drug delivery system (DDS) based on RGD-PEG-PUSeSe-PEG-RGD self-assembling micelles for imaging-guided gemcitabine (GEM) chemosensitization and anti-recurrence/metastasis therapy. The diselenide-containing micelles were degraded in response to TrxR stimuli for GEM releasing. In the meantime, the dissociated polymers′ chain segments targeted the active site of TrxR via Se-Se/Se-S dynamic reactions for activity inhibition. This inhibition by the micelles not only provided chemosensitization, but reduced tumor recurrence/metastasis risk via the induction of residual tumor cell apoptosis by triggering ROS production post-chemotherapy. In this work, we took the transformation between Se-containing dynamic covalent bonds developed by our group from in vitro to in vivo, which furthered the knowledge on the biochem. of selenium and provided aspects to develop new TrxR inhibitors. Overall, the TrxR-interfering DDS combined excellent antitumor effects for primary solid tumors with the inhibition of tumor recurrence/metastasis during post-treatment care, providing new perspectives for efficient cancer therapy. After reading the article, we found that the author used 3-Bromopropan-1-ol(cas: 627-18-9Electric Literature of C3H7BrO)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Electric Literature of C3H7BrO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Straightforward convergent access to 2-arylated polysubstituted benzothiazoles》 was published in Tetrahedron in 2020. These research results belong to Sadek, Omar; Perrin, David M.; Gras, Emmanuel. Application In Synthesis of 2-Hydroxyphenylboronic acid The article mentions the following:

A modular access to 2,4-disubstituted benzothiazoles I [R = 2-hydroxyphenyl, 2-aminophenyl, 1-[(tert-butoxy)carbonyl]-1H-indol-2-yl; R1 = Br, 2-aminophenyl] has been achieved though the intermediacy of 4-bromo-2-iodobenzothiazole. The difference in reactivity of both halogens was advantageously exploited to achieve sequential Suzuki-Miyaura cross-coupling giving access to a range of polyaromatic derivatives II [R2 = OH, NH2; R3 = 2-hydroxyphenyl, 2-(methylamino)phenyl, 1H-indol-2-yl] featuring a central benzothiazole core. In the experiment, the researchers used many compounds, for example, 2-Hydroxyphenylboronic acid(cas: 89466-08-0Application In Synthesis of 2-Hydroxyphenylboronic acid)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Application In Synthesis of 2-Hydroxyphenylboronic acid

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Iridium-catalyzed transfer hydrogenation of ketones and aldehydes using glucose as a sustainable hydrogen donor》 were Yoshida, Masato; Hirahata, Ryota; Inoue, Takayoshi; Shimbayashi, Takuya; Fujita, Ken-ichi. And the article was published in Catalysts in 2019. Recommanded Product: 873-75-6 The author mentioned the following in the article:

A new catalytic system for transfer hydrogenation of carbonyl compounds using glucose as a hydrogen donor was developed. Various ketones and aldehydes were efficiently converted to corresponding alcs. with two equivalent of glucose in the presence of a small amount (0.1 to 1.0 mol%) of iridium catalyst that had a functional ligand. In this catalytic system, transfer hydrogenation reactions proceeded based on the cooperativity of iridium and a functional ligand. It should be noted that environmentally benign water was used as a solvent in the present catalytic system for the reduction of various carbonyl substrates. Furthermore, the reaction scope was extended by using N,N-dimethylacetamide as a reaction solvent. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Recommanded Product: 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Recommanded Product: 873-75-6 It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Synthesis of Chiral Triazole-Based Halogen Bond Donors》 were Kaasik, Mikk; Kaabel, Sandra; Kriis, Kadri; Jarving, Ivar; Kanger, Tonis. And the article was published in Synthesis in 2019. Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol The author mentioned the following in the article:

The simple click chem. was applied for the straightforward synthesis of enantiomerically pure mono- and bidentate as well as multifunctional iodotriazole-based halogen bond donors I [R1 = (R,R)-2-acylaminocyclohexyl, acyl = MeCO, t-BuCO, PhCO, R2 = Ph; R1 = (1S,2R)-2-hydroxyindenyl, L-menthyl; R2 = 3,5-(F3C)2C6H3; etc.] and II. The methodol. is characterized by a wide variability due to easy access to chiral azides. In addition to this study using (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, there are many other studies that have used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Tetrahedron included an article by Li, Hai-Jun; Mellerup, Soren K.; Wang, Xiang; Wang, Suning. Related Products of 89466-08-0. The article was titled 《Impact of intramolecular H bond and n-π* interactions on photophysical and CO2 sensing properties of laterally appended D-π-A triarylboron compounds》. The information in the text is summarized as follows:

Several examples of laterally appended donor-π-acceptor (D-π-A) B compounds based on a biphenyl unit were synthesized and fully characterized. Intramol. H bonds or n-π* interactions have a great impact on the photophys./fluorescent properties of these compounds Some members of these compounds display fluorescent response toward CO2. In the experiment, the researchers used many compounds, for example, 2-Hydroxyphenylboronic acid(cas: 89466-08-0Related Products of 89466-08-0)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Related Products of 89466-08-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Organic Letters included an article by Yi, Jun; Badir, Shorouk O.; Kammer, Lisa Marie; Ribagorda, Maria; Molander, Gary A.. Application In Synthesis of trans-4-Aminocyclohexanol. The article was titled 《Deaminative Reductive Arylation Enabled by Nickel/Photoredox Dual Catalysis》. The information in the text is summarized as follows:

Described is a cross-electrophilic, deaminative coupling strategy harnessing Katritzky salts as a new species of electrophile in Ni/photoredox dual catalytic reductive cross-coupling reactions. Distinguishing features of this arylation protocol include its mild reaction conditions, high chemoselectivity, and adaptability to a variety of complex substrates [i.e., pyridinium salts derived from amines and partners derived from (hetero)aryl bromides]. In the experiment, the researchers used trans-4-Aminocyclohexanol(cas: 27489-62-9Application In Synthesis of trans-4-Aminocyclohexanol)

trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Application In Synthesis of trans-4-Aminocyclohexanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,RSC Advances included an article by Ma, Weimin; Huang, Jiawei; Li, Chao; Jiang, Yueren; Li, Baolin; Qi, Ting; Zhu, Xiaozhang. Category: alcohols-buliding-blocks. The article was titled 《One-pot synthesis and property study on thieno[3,2-b]furan compounds》. The information in the text is summarized as follows:

Based on the regioselective intermol. Suzuki coupling and subsequent intramol. Ullmann C-O coupling reactions, one-pot synthesis of benzo[4,5]thieno[3,2-b]benzofurans I (R1 = H, 3-Cl, 2-n-octyl; R2 = H, 8-F, 8-Me, 7-t-Bu) was developed after optimization of the reaction conditions including catalysts, solvents, bases, ligands and reaction times. The one-pot reaction, with only 2 mol% Pd(PPh3)4 and 2 mol% copper(I) thiophene-2-carboxylate as the catalysts, K3PO4·3H2O as the base and tert-butanol as the solvent, afforded moderate to good yields (up to 70%) for a variety of substrates. The experimental part of the paper was very detailed, including the reaction process of 2-Hydroxyphenylboronic acid(cas: 89466-08-0Category: alcohols-buliding-blocks)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Quantification of vegetable oil in recycled paper》 were Ntifafa, Yao; Szajda-Lam, Maria; Ghosh, Ashok; Hart, Peter W.. And the article was published in Tappi Journal in 2020. Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol The author mentioned the following in the article:

Vegetable soybean oil is commonly used in cooking foods that are packaged in takeaway paperboard containers. Vegetable oil is hydrophobic, and in sufficiently high concentration, could interfere with interfiber bonding and result in paper strength loss. In order to quantify the effect of oil on the resulting paperboard strength, it is necessary to quantify the oil content in paper. A lab method was evaluated to determine the soybean oil content in paper. Handsheets were made with pulps previously treated with different proportions of vegetable oil. Pyrolysis gas chromatog.-mass spectrometry (pyGCMS) was used to quantify the amount of oil left in the handsheets. The results revealed a strong correlation between the amount of oil applied to the initial pulp and the amount of oil left in the handsheets. In addition, the effect of vegetable oils on paper strength may be affected by the cooking process. Vegetable oil is known to degrade over time in the presence of oxygen, light, and temperature The vegetable oil was put in an oven to imitate the oil lifecycle during a typical pizza cooking process. The cooked oil was then left at room temperature and not protected from air (oxygen) or from normal daylight. The heated, then cooled, oil was stored over a period of 13 wk. During this time, samples of the aged oil were tested as part of a time-based degradation study of the cooked and cooled oil. In addition to this study using rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol, there are many other studies that have used rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol) was used in this study.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts