Tag: 100-200

Zhou, Shan-Shan et al. published their research in Journal of Pharmaceutical and Biomedical Analysis in 2017 | CAS: 10030-85-0

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C6H14O6

Synchronous characterization of carbohydrates and ginsenosides yields deeper insights into the processing chemistry of ginseng was written by Zhou, Shan-Shan;Xu, Jun;Kong, Ming;Yip, Ka-Man;Xu, Jin-Di;Shen, Hong;Zhao, Zhong-Zhen;Li, Song-Lin;Chen, Hu-Biao. And the article was included in Journal of Pharmaceutical and Biomedical Analysis in 2017.COA of Formula: C6H14O6 This article mentions the following:

Carbohydrates and ginsenosides in ginseng are biol. interrelated. Their synchronous anal. is therefore essential in chem. research on ginseng to characterize its “holistic” quality. Here we investigated the processing chem. of red ginseng (RG), a ginseng product processed by water-steaming, for which both carbohydrates and ginsenosides were qual. and quant. determined through multiple anal. techniques. Results revealed that the steam-processing not only qual. and quant. altered the ginsenosides but also affected the polymeric carbohydrates via changing their physiochem. parameters, i.e. water-solubility, mol. size, types and ratios of constituent monosaccharides. Potential mechanisms involved in the transformation of ginseng chems. are proposed and discussed, including hydrolysis (deglycosylation, demalonylation, deacetylation), dehydration, polymerization, volatilization, reduction and the Maillard reaction. The study strengthens the research on the processing chem. of RG, and therefore should be helpful for elucidating the scientific basis of RG preparation and application. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0COA of Formula: C6H14O6).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C6H14O6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhao, Xiangyu et al. published their research in Organic Letters in 2018 | CAS: 29364-29-2

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of Sodium 2-methyl-2-propanethiolate

Highly β(Z)-Selective Hydrosilylation of Terminal Alkynes Catalyzed by Thiolate-Bridged Dirhodium Complexes was written by Zhao, Xiangyu;Yang, Dawei;Zhang, Yahui;Wang, Baomin;Qu, Jingping. And the article was included in Organic Letters in 2018.Application In Synthesis of Sodium 2-methyl-2-propanethiolate This article mentions the following:

A series of novel monothiolate-bridged dirhodium complexes, [Cp*Rh(μ-SR)(μ-Cl)2RhCp*][BF4] {Cp* = η5-C5Me5, R = tert-Bu (tBu), 1a; R = ferrocenyl (Fc), 1b; R = adamantyl (Ad), 1c} were designed and successfully synthesized, which can smoothly facilitate highly regioselective and stereoselective hydrosilylation of terminal alkynes to afford β(Z) vinylsilanes with good functional group compatibility. Furthermore, the hydride bridged dirhodium complex [Cp*Rh(μ-StBu)(μ-Cl)(μ-H)RhCp*][BF4] (5) as a potential intermediate was obtained by the reaction of 1a with excess HSiEt3. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Application In Synthesis of Sodium 2-methyl-2-propanethiolate).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of Sodium 2-methyl-2-propanethiolate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Behrman, E. J. et al. published their research in Organic Reactions (Hoboken, NJ, United States) in 1988 | CAS: 52010-89-6

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C8H8O3

The persulfate oxidation of phenols and arylamines (the Elbs and the Boyland-Sims oxidations) was written by Behrman, E. J.. And the article was included in Organic Reactions (Hoboken, NJ, United States) in 1988.Synthetic Route of C8H8O3 The following contents are mentioned in the article:

A review of the article The persulfate oxidation of phenols and arylamines (the Elbs and the Boyland-Sims oxidations). This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Synthetic Route of C8H8O3).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C8H8O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Patel, Suhani J. et al. published their research in Industrial & Engineering Chemistry Research in 2010 | CAS: 115-84-4

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol

QSPR Flash Point Prediction of Solvents Using Topological Indices for Application in Computer Aided Molecular Design. [Erratum to document cited in CA151:127086] was written by Patel, Suhani J.;Ng, Dedy;Mannan, M. Sam. And the article was included in Industrial & Engineering Chemistry Research in 2010.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

The neural network algorithms are modified as is the data in the tables. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Quality Control of 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Baker, Stephen J. et al. published their research in Journal of Medicinal Chemistry in 2006 | CAS: 174671-93-3

7-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol (cas: 174671-93-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.COA of Formula: C7H6BFO2

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis was written by Baker, Stephen J.;Zhang, Yong-Kang;Akama, Tsutomu;Lau, Agnes;Zhou, Huchen;Hernandez, Vincent;Mao, Weimin;Alley, M. R. K.;Sanders, Virginia;Plattner, Jacob J.. And the article was included in Journal of Medicinal Chemistry in 2006.COA of Formula: C7H6BFO2 The following contents are mentioned in the article:

A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small mol., AN2690 (I), which is currently in clin. trials for onychomycosis topical treatment. This study involved multiple reactions and reactants, such as 7-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol (cas: 174671-93-3COA of Formula: C7H6BFO2).

7-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol (cas: 174671-93-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.COA of Formula: C7H6BFO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Baker, Stephen J. et al. published their research in Journal of Medicinal Chemistry in 2006 | CAS: 174671-93-3

7-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol (cas: 174671-93-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Electric Literature of C7H6BFO2

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis was written by Baker, Stephen J.;Zhang, Yong-Kang;Akama, Tsutomu;Lau, Agnes;Zhou, Huchen;Hernandez, Vincent;Mao, Weimin;Alley, M. R. K.;Sanders, Virginia;Plattner, Jacob J.. And the article was included in Journal of Medicinal Chemistry in 2006.Electric Literature of C7H6BFO2 The following contents are mentioned in the article:

A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small mol., AN2690 (I), which is currently in clin. trials for onychomycosis topical treatment. This study involved multiple reactions and reactants, such as 7-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol (cas: 174671-93-3Electric Literature of C7H6BFO2).

7-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol (cas: 174671-93-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Electric Literature of C7H6BFO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cole, Moses M. et al. published their research in Journal of Economic Entomology in 1951 | CAS: 115-84-4

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C9H20O2

Field tests of selected repellents against the American dog tick was written by Cole, Moses M.;Lloyd, George W.. And the article was included in Journal of Economic Entomology in 1951.COA of Formula: C9H20O2 The following contents are mentioned in the article:

Dibutyl adipate, a mixture of 2-butyl-2-ethyl-1,3-propanediol (I), benzyl benzoate (II), and N-butylacetanilide (III), a mixture of N-butyl-4-cyclohexane-1,2-dicarboximide (IV), undecylenic acid (V), and III, and a mixture of IV, V, I, III, and II gave 97-99.6% repellency against Dermacentor variabilis. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4COA of Formula: C9H20O2).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C9H20O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Philippov, Alexey A. et al. published their research in Mendeleev Communications in 2019 | CAS: 106-21-8

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application of 106-21-8

Simple H2-free hydrogenation of unsaturated monoterpenoids catalyzed by Raney nickel was written by Philippov, Alexey A.;Chibiryaev, Andrey M.;Martyanov, Oleg N.. And the article was included in Mendeleev Communications in 2019.Application of 106-21-8 The following contents are mentioned in the article:

A series of monoterpenoids (citral, carvone, menthone, camphor) as well as cyclohexanone and hex-5-en-2-one were subjected to transfer hydrogenation with PriOH/Raney nickel system at 82 or 150 °C. Among monoterpenoids, citral and carvone underwent full conversion at 82 °C within 5 h. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Application of 106-21-8).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application of 106-21-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gilbert, I. H. et al. published their research in Florida Entomologist in 1953 | CAS: 115-84-4

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol

All-purpose repellent mixtures as clothing treatments against chiggers was written by Gilbert, I. H.;Gouck, H. K.. And the article was included in Florida Entomologist in 1953.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

A mixture containing benzyl benzoate 29.7, butylacetanilide 29.7, 2-butyl-2-ethyl-1,3-propanediol 29.7, and lindane 1.0% applied at the rate of 3.6 g./sq. ft. of cloth was the most effective repellant of 11 reported. With an average of 4 soap and water washings, 100% protection was maintained. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mehta, Goverdhan et al. published their research in Tetrahedron Letters in 2010 | CAS: 52010-89-6

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 52010-89-6

Total synthesis of the fungal metabolite (±)-acremine G: acceleration of a biomimetic Diels-Alder reaction on silica gel was written by Mehta, Goverdhan;Babu Khan, Tabrez;Sunil Kumar, Y. C.. And the article was included in Tetrahedron Letters in 2010.Recommanded Product: 52010-89-6 The following contents are mentioned in the article:

A total synthesis of the bioactive tetracyclic natural product acremine G has been achieved in which a regio- and stereoselective biomimetic Diels-Alder reaction between two readily assembled building blocks, accelerated on a solid support (silica gel), forms the key step. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Recommanded Product: 52010-89-6).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 52010-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts