Category: alcohols-buliding-blocks

Luo, Nianhua published the artcileHighly Selective Hydroxylation and Alkoxylation of Silanes: One-Pot Silane Oxidation and Reduction of Aldehydes/Ketones, Application In Synthesis of 17877-23-5, the publication is Organometallics (2020), 39(1), 165-171, database is CAplus.

An efficient chemoselective iridium-catalyzed method for the hydroxylation and alkoxylation of organosilanes to generate hydrogen gas and silanols or silyl ethers was developed. A variety of sterically hindered silanes with alkyl, aryl, and ether groups were tolerated. Furthermore, this atom-economical catalytic protocol can be used for the synthesis of silanediols and silanetriols. A one-pot silane oxidation and chemoselective reduction of aldehydes/ketones was also realized.

Organometallics published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Application In Synthesis of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Luo, Nianhua published the artcileHighly Selective Hydroxylation and Alkoxylation of Silanes: One-Pot Silane Oxidation and Reduction of Aldehydes/Ketones, Synthetic Route of 597-52-4, the publication is Organometallics (2020), 39(1), 165-171, database is CAplus.

An efficient chemoselective iridium-catalyzed method for the hydroxylation and alkoxylation of organosilanes to generate hydrogen gas and silanols or silyl ethers was developed. A variety of sterically hindered silanes with alkyl, aryl, and ether groups were tolerated. Furthermore, this atom-economical catalytic protocol can be used for the synthesis of silanediols and silanetriols. A one-pot silane oxidation and chemoselective reduction of aldehydes/ketones was also realized.

Organometallics published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Synthetic Route of 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nikitin, Sergei published the artcileLignin-Inspired Polybenzylethersulfone Synthesis via S_NAr Reaction, Related Products of alcohols-buliding-blocks, the publication is Macromolecular Chemistry and Physics (2022), 223(13), 2100484, database is CAplus.

A new type of lignin-inspired polybenzylethersulfone (PBES) is synthesized by S_NAr reaction in 75% yield. Success of the polymerization is confirmed by ATR-IR, ¹H, ¹³C NMR spectroscopy and MALDI-TOF MS. The obtained polysulfone is solvent casted into a film which displays high thermal and chem. stability. Treatment with 33% HBr in acetic acid leads to degradation of the material. The isolated degradation products are identified and repolymd. back into PBES demonstrating the opportunity for chem. recycling of this new polymer.

Macromolecular Chemistry and Physics published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bender, Christoph published the artcileStereoselective 1-arylation of isoquinolines via chiral N-acylisoquinolinium salts, Quality Control of 27292-49-5, the publication is ARKIVOC (Gainesville, FL, United States) (2008), 111-136, database is CAplus.

Reaction of isoquinolines with (R)-menthyl chlorocarbonate or (S)-α-Cbz-aminoacyl fluorides and arenes or heteroarenes gave access to the corresponding 2-R¹-1-R²-1,2-dihydroisoquinolines I [R¹ = H, Br, Ph, 4-ClC₆H₄; R² = menthyloxycarbonyl, N-benzyloxycarbonyl-2-amino-3-phenylpropionyl, N-benzyloxycarbonyl-2-amino-propionyl; R³ = 4-(1-dimethylaminonaphthyl), 4-Et₂NC₆H₄, 3-indolyl, etc.] in a Mannich-type reaction via intermediate N-acylisoquinolinium salts. As an alternative, aryl metal compounds could be used. Modest stereoselectivities were achieved. Further reduction and hydrolysis of the products gave access to 1,2,3,4-tetrahydroisoquinolines II (R² = H, Me; R³ = Ph, 4-Et₂NC₆H₄, 3-MeOC₆H₄, 4-MeOC₆H₄, 3-indolyl).

ARKIVOC (Gainesville, FL, United States) published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C10H13NO2, Quality Control of 27292-49-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Dungai published the artcileLiBr-Catalyzed C3-Disulfuration between Indole and N-Dithiophthalimide, Recommanded Product: 2-Phenylethanethiol, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A simple, green halide-catalyzed protocol for disulfuration of indole derivatives with N-dithiophthalimides was developed. This C-H disulfide reaction proceeded smoothly at room temperature with economical LiBr as catalyst, providing an effective method for the synthesis of novel unsym. disulfides. A series of 3-dithioindole derivatives were obtained in high yields with good functional group tolerance, moreover, the wide scope of Harpp reagents (aryl, benzyl, primary, secondary, tertiary) confirmed the practicability of this approach.

Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C2H2N4O2, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xu, Zhiqiang published the artcileResearch on cement hydration and hardening with different alkanolamines, Product Details of C9H21NO3, the publication is Construction and Building Materials (2017), 296-306, database is CAplus.

In this work, six types of alkanolamines (i.e., TEA, TIPA, DEIPA, EDIPA, THEED and THPED) were added into Portland cement as chem. additives, and their effects on phys. properties and hydration of Portland cement as well as mechanism were investigated. The results show that all the alkanolamines expect TEA can effectively improve the degree of cement hydration. TEA delays the hydration of alite because the formation of the TEA-Ca2+ complex inhibits the growth of CH. TIPA accelerates the hydration of C4AF at late stage, but reduce the early strength due to its air-entraining effect. The lower dosages of DEIPA and EDIPA have the advantages of TEA and TIPA, which increase not only the early strength but also the late strength. They promote both the hydration of the aluminum and ferrite phase as well as catalyze the conversion of AFt to AFm, which lead to the optimization of pore size distribution. The effects of THEED and THPED on hydration of Portland cement are similar though their mol. structure are different which improve the late strength and have larger suitable dosage range.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C10H23N, Product Details of C9H21NO3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xu, Zhiqiang published the artcileHydration of Portland cement with alkanolamines by thermal analysis, Product Details of C9H21NO3, the publication is Journal of Thermal Analysis and Calorimetry (2018), 131(1), 37-47, database is CAplus.

Four types of alkanolamines (i.e., traditional alkanolamines represented by TEA and TIPA and new alkanolamines represented by DEIPA and EDIPA) were added to Portland cement as chem. additives, and their effects on the cement properties and hydration process were investigated. An isothermal calorimeter was used to track the hydration heat flow of the cement pastes with or without alkanolamines. Thermogravimetric analyses were performed to measure the degree of hydration over the course of 28 days. In addition, X-ray diffraction, MIP anal. and SEM were used as auxiliary tests. The results indicated that alkanolamines improved the compressive strength of the cement mortars. It was found that TEA increased the rate of the second hydration of C₃A, and TIPA accelerated the hydration of C₄AF. DEIPA and EDIPA promoted the hydration of both the aluminum and ferrite phases as well as catalyzed the conversion of AFt to the AFm phase. By contrast, the new alkanolamines represented by DEIPA and EDIPA expressed more superior properties.

Journal of Thermal Analysis and Calorimetry published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Product Details of C9H21NO3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kalinoski, Ryan M. published the artcileAntimicrobial Properties of Corn Stover Lignin Fractions Derived from Catalytic Transfer Hydrogenolysis in Supercritical Ethanol with a Ru/C Catalyst, HPLC of Formula: 645-56-7, the publication is ACS Sustainable Chemistry & Engineering (2020), 8(50), 18455-18467, database is CAplus.

Converting lignin to value added products at high yields provides an avenue for making ethanol biorefineries more profitable while reducing the carbon footprint of products generally derived from petroleum. In this study, corn stover lignin was depolymerized by catalytic transfer hydrogenolysis (CTH) in supercritical ethanol with a Ru/C catalyst. The lignin derived bio-oil was then sequentially extracted utilizing hexane, petroleum ether, chloroform and Et acetate as solvents in order of less polar to polar and the subsequent bio-oils were characterized using GPC, GC/MS and HSQC NMR. Results show lignin derived compounds were sequentially extracted into groups depending on the solvent polarity. Antimicrobial properties of the bio-oils were screened against Gram-pos. (Bacillus subtilis, Lactobacillus amylovorus, and Staphylococcus epidermidis), Gram-neg. (Escherichia coli) bacteria and yeast (Saccharomyces cerevisiae) by examining microbial growth inhibition. Results show that CTH derived bio-oils inhibited all tested organisms at concentrations less than 3 mg/mL. Total monomer concentration and the presence of specific monomers (i.e., syringyl propane) showed correlations to antimicrobial activity, likely due to cell death or membrane damage. This study provides insights into using sequential extraction to fractionate lignin-derived compounds and correlations between the properties of the extracted compounds and their antimicrobial activity. A lignin-based bio-oil was prepared from catalytic transfer hydrogenolysis of purified corn stover lignin with ethanol and a ruthenium on carbon catalyst. Polar and nonpolar solvents were used to sequentially extract different compounds The raw bio-oil and sequential extraction fractions exhibited antimicrobial properties against Gram-pos./neg. bacteria and yeast, with activity related to total monomer content and specific monomers.

ACS Sustainable Chemistry & Engineering published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C9H12O, HPLC of Formula: 645-56-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shen, Changcheng published the artcileValorization of lignin in native corn stover via fractionation-hydrogenolysis process over cobalt-supported catalyst without external hydrogen, Related Products of alcohols-buliding-blocks, the publication is Molecular Catalysis (2021), 111832, database is CAplus.

Lignin, which represents the most abundant renewable aromatic biomass resource on the earth, is promising as an alternative for the production of chems. We presented a modified method that provides the hydrogen source in the reaction with a mixed solvent of alc., acid and water, replacing the original method that directly provides a hydrogen source with external hydrogen. In addition, a new cobalt supported on nitrogen doped carbon catalyst preparation method (one-pot) was presented. We proposed one-step method in which corn stover lignin is converted to target monomers over Co/AC-N_one-pot catalyst and mixed solvent. The role of the alc. to acid and water mixed solvent not only extract lignin fragments from the matrix but also provide the hydrogen source. Cobalt which has electronic interaction with the nitrogen reformed alcs. to obtain hydrogen and stabilized lignin intermediates during the reaction by hydrogenation of active bonds. Different kinds of nitrogen including pyridinic and pyrrolic nitrogen functional groups plays a critical role in stabilizing Co. Nearly complete delignification (91%) and high yield of target monomers (23.8%) can be obtained under the conditions (5wt% Co/Ac-N_one-pot, 10:1:1mixt. solvent consist of isopropanol/water/ formic acid, 235°C, 200 min, 0.1 MPa N₂), and the selectivity of target monomers was 85%. Circulation experiment of catalyst was performed directly without any operation of the residue, and it could maintain 90% activity in the first four cycles.

Molecular Catalysis published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C15H20O6, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Y. published the artcileIn vitro interactions of ambroxol hydrochloride or amlodipine in combination with antibacterial agents against carbapenem-resistant Acinetobacter baumannii, Related Products of alcohols-buliding-blocks, the publication is Letters in Applied Microbiology (2020), 70(3), 189-195, database is CAplus and MEDLINE.

The aim of this study was to investigate the in vitro interactions of ambroxol hydrochloride (ABH) or amlodipine (AML) with commonly used antibacterial agents, including meropenem, imipenem-cilastatin sodium, biapenem, cefoperazone-sulbactam, polymyxin B, and tigecycline, against six carbapenem-resistant Acinetobacter baumannii (CRAB) clin. isolates. Drug interactions were interpreted using two models, i.e., the fractional inhibitory concentration index (FICI) model and the percentage of growth difference (ΔE) model. The results show that a majority of the combination groups exhibited partial synergy and additive interactions, such as the combinations of carbapenems and cefoperazone-sulbactam (SCF) with ABH or AML. While the combination of PB/AML exhibited synergistic interactions against all tested isolates, and PB/ABH exhibited synergistic interactions against two isolates. The FICI and ΔE model correlated very well for the combinations of PBABH and PB/AML against AB2. The combinations of TGC with ABH or AML mainly exhibited additive and indifferent interactions. There were no antagonistic interactions observed in any of the combinations. In conclusion, this study revealed that the non-antibacterial agents ABH or AML can work synergistically or partial synergistically with antibacterial agents against CRAB. This finding is crucial for overcoming the carbapenem resistance of A. baumannii.

Letters in Applied Microbiology published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C12H25Br, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts